# Phase I Study of RO4929097, a Gamma Secretase Inhibitor of Notch Signaling, in Patients With Refractory Metastatic or Locally Advanced Solid Tumors

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/phase-i-study-of-ro4929097-a-gamma-secretase-inhibitor-of-notch-signaling-in/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Anthony W. Tolcher,Wells A. Messersmith,Stanislaw M. Mikulski,Kyriakos P. Papadopoulos,Eunice L. Kwak,Darlene Gibbon,Amita Patnaik,Gerald S. Falchook,Arvind Dasari,Geoffrey I. Shapiro,John F. Boylan,Zhi-Xin Xu,Ka Wang,Astrid Koehler,James Song,Steven A. Middleton,Jonathan Deutsch,Mark DeMario,Razelle Kurzrock,Jennifer J. Wheler |
| Citations | 280 |
| DOI | 10.1200/jco.2011.36.8282 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2011.36.8282 |
| OpenAlex ID | https://openalex.org/W2126959323 |
| PMID | 22529266 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Arvind Dasari](https://scholariq.org/researchers/arvind-dasari/)

## Paper journal

- [Journal of Clinical Oncology](https://scholariq.org/journals/journal-of-clinical-oncology/)

## Paper primary topic

- [Developmental Biology and Gene Regulation](https://scholariq.org/topics/developmental-biology-and-gene-regulation/)

## Paper topics

- [Developmental Biology and Gene Regulation](https://scholariq.org/topics/developmental-biology-and-gene-regulation/)
- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)
- [Cancer Cells and Metastasis](https://scholariq.org/topics/cancer-cells-and-metastasis/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.