# PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor–positive breast cancer

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/pi3k-inhibition-results-in-enhanced-estrogen-receptor-function-and-dependence-in/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Ana Bosch,Zhiqiang Li,Anna Bergamaschi,Haley Ellis,Eneda Toska,Aleix Prat,Jessica J. Tao,Daniel E. Spratt,Nerissa T. Viola,Pau Castel,Gerard Minuesa,Natasha Morse,Jordi Rodón,Yasir H. Ibrahim,Javier Cortés,José Manuel Pérez-García,Patricia Galván,Judit Grueso,Marta Guzmán,John A. Katzenellenbogen,Michael G. Kharas,Jason S. Lewis,Maura N. Dickler,Violeta Serra,Neal Rosen,Sarat Chandarlapaty,Maurizio Scaltriti,José Baselga |
| Citations | 440 |
| DOI | 10.1126/scitranslmed.aaa4442 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2102004296 |
| PMID | 25877889 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Maura N. Dickler](https://scholariq.org/researchers/maura-n-dickler/)
- [Daniel E. Spratt](https://scholariq.org/researchers/daniel-e-spratt/)

## Paper primary topic

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

## Paper topics

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Advanced Breast Cancer Therapies](https://scholariq.org/topics/advanced-breast-cancer-therapies/)
- [Estrogen and related hormone effects](https://scholariq.org/topics/estrogen-and-related-hormone-effects/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.