# PIK3CA/PTEN Mutations and Akt Activation As Markers of Sensitivity to Allosteric mTOR Inhibitors

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/pik3ca-pten-mutations-and-akt-activation-as-markers-of-sensitivity-to-allosteric/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Funda Meric‐Bernstam,Argun Akçakanat,Huiqin Chen,Kim‐Anh Do,Takafumi Sangai,Farrell Adkins,Ana M. González-Angulo,Asif Rashid,Katherine Crosby,Mei Dong,Alexandria T. Phan,Robert A. Wolff,Sanjay Gupta,Gordon B. Mills,James C. Yao |
| Citations | 208 |
| DOI | 10.1158/1078-0432.ccr-11-2123 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://clincancerres.aacrjournals.org/content/clincanres/18/6/1777.full.pdf |
| OpenAlex ID | https://openalex.org/W2110059026 |
| PMID | 22422409 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Farrell Adkins](https://scholariq.org/researchers/farrell-adkins/)
- [James C. Yao](https://scholariq.org/researchers/james-c-yao/)

## Paper journal

- [Clinical Cancer Research](https://scholariq.org/journals/clinical-cancer-research/)

## Paper primary topic

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

## Paper topics

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Tuberous Sclerosis Complex Research](https://scholariq.org/topics/tuberous-sclerosis-complex-research/)
- [Neuroendocrine Tumor Research Advances](https://scholariq.org/topics/neuroendocrine-tumor-research-advances/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.