# Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Induces Apoptosis and Cell Cycle Arrest in A549 Cells through p53 Accumulation via c-Jun NH2-Terminal Kinase-Mediated Phosphorylation at Serine 15 in Vitro and in Vivo

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/plumbagin-5-hydroxy-2-methyl-1-4-naphthoquinone-induces-apoptosis-and-cell-cycle/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Ya‐Ling Hsu,Chien-Yu Cho,Po‐Lin Kuo,Yu‐Ting Huang,Chun‐Ching Lin |
| Citations | 208 |
| DOI | 10.1124/jpet.105.098863 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine,Pharmacology, Toxicology and Pharmaceutics |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W1982258251 |
| PMID | 16632641 |
| Type | article |
| Year | 2006 |

## Paper authors

- [Yu‐Ting Huang](https://scholariq.org/researchers/yu-ting-huang/)

## Paper primary topic

- [Bioactive Compounds and Antitumor Agents](https://scholariq.org/topics/bioactive-compounds-and-antitumor-agents/)

## Paper topics

- [Bioactive Compounds and Antitumor Agents](https://scholariq.org/topics/bioactive-compounds-and-antitumor-agents/)
- [Cancer-related Molecular Pathways](https://scholariq.org/topics/cancer-related-molecular-pathways/)
- [Cell death mechanisms and regulation](https://scholariq.org/topics/cell-death-mechanisms-and-regulation/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.