# Polyclonal Secondary <i>FGFR2</i> Mutations Drive Acquired Resistance to FGFR Inhibition in Patients with FGFR2 Fusion–Positive Cholangiocarcinoma

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/polyclonal-secondary-i-fgfr2-i-mutations-drive-acquired-resistance-to-fgfr/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Lipika Goyal,Supriya K. Saha,Leah Y. Liu,Giulia Siravegna,Ignaty Leshchiner,Leanne G. Ahronian,Jochen K. Lennerz,Phuong Vu,Vikram Deshpande,Avinash Kambadakone,Benedetta Mussolin,Stephanie Reyes,Laura E. Henderson,Jiaoyuan Elisabeth Sun,Emily E. Van Seventer,Joseph M. Gurski,Sabrina Baltschukat,Barbara Schacher-Engstler,Louise Barys,Christelle Stamm,Pascal Furet,David P. Ryan,James R. Stone,A. John Iafrate,Gad Getz,Diana Graus Porta,Ralph Tiedt,Alberto Bardelli,Dejan Juric,Ryan B. Corcoran,Nabeel Bardeesy,Andrew X. Zhu |
| Citations | 550 |
| DOI | 10.1158/2159-8290.cd-16-1000 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | http://cancerdiscovery.aacrjournals.org/content/early/2016/12/29/2159-8290.CD-16-1000.long |
| OpenAlex ID | https://openalex.org/W2566575334 |
| PMID | 28034880 |
| Type | article |
| Year | 2016 |

## Paper authors

- [Jochen K. Lennerz](https://scholariq.org/researchers/jochen-k-lennerz/)
- [A. John Iafrate](https://scholariq.org/researchers/a-john-iafrate/)

## Paper journal

- [Cancer Discovery](https://scholariq.org/journals/cancer-discovery/)

## Paper primary topic

- [Cholangiocarcinoma and Gallbladder Cancer Studies](https://scholariq.org/topics/cholangiocarcinoma-and-gallbladder-cancer-studies/)

## Paper topics

- [Cholangiocarcinoma and Gallbladder Cancer Studies](https://scholariq.org/topics/cholangiocarcinoma-and-gallbladder-cancer-studies/)
- [Fibroblast Growth Factor Research](https://scholariq.org/topics/fibroblast-growth-factor-research/)
- [Cancer Genomics and Diagnostics](https://scholariq.org/topics/cancer-genomics-and-diagnostics/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.