# PTEN Loss Mediates Clinical Cross-Resistance to CDK4/6 and PI3Kα Inhibitors in Breast Cancer

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/pten-loss-mediates-clinical-cross-resistance-to-cdk4-6-and-pi3k-inhibitors-in/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Carlotta Costa,Ye Wang,Amy Ly,Yasuyuki Hosono,Ellen Murchie,Charlotte S. Walmsley,Tiffany G. Huynh,Christopher Healy,Rachel Peterson,Shogo Yanase,Charles T. Jakubik,Laura E. Henderson,Leah J. Damon,Daria Timonina,Ioannis Sanidas,Christopher J. Pinto,Mari Mino–Kenudson,James R. Stone,Nicholas J. Dyson,Leif W. Ellisen,Aditya Bardia,Hiromichi Ebi,Cyril H. Benes,Jeffrey A. Engelman,Dejan Juric |
| Citations | 272 |
| DOI | 10.1158/2159-8290.cd-18-0830 |
| Fields | Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://cancerdiscovery.aacrjournals.org/content/candisc/10/1/72.full.pdf |
| OpenAlex ID | https://openalex.org/W2980008739 |
| PMID | 31594766 |
| Type | article |
| Year | 2019 |

## Paper authors

- [Mari Mino–Kenudson](https://scholariq.org/researchers/mari-mino-kenudson/)
- [Hiromichi Ebi](https://scholariq.org/researchers/hiromichi-ebi/)
- [Jeffrey A. Engelman](https://scholariq.org/researchers/jeffrey-a-engelman/)

## Paper journal

- [Cancer Discovery](https://scholariq.org/journals/cancer-discovery/)

## Paper primary topic

- [Advanced Breast Cancer Therapies](https://scholariq.org/topics/advanced-breast-cancer-therapies/)

## Paper topics

- [Advanced Breast Cancer Therapies](https://scholariq.org/topics/advanced-breast-cancer-therapies/)
- [Cancer-related Molecular Pathways](https://scholariq.org/topics/cancer-related-molecular-pathways/)
- [Chronic Lymphocytic Leukemia Research](https://scholariq.org/topics/chronic-lymphocytic-leukemia-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.