# Pyrazole-4-Carboxamide (YW2065): A Therapeutic Candidate for Colorectal Cancer via Dual Activities of Wnt/β-Catenin Signaling Inhibition and AMP-Activated Protein Kinase (AMPK) Activation

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/pyrazole-4-carboxamide-yw2065-a-therapeutic-candidate-for-colorectal-cancer-via/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Wei Yang,Yingjun Li,Yong Ai,Obinna N. Obianom,Dong Guo,Hong Yang,Srilatha Sakamuru,Menghang Xia,Yan Shu,Fengtian Xue |
| Citations | 43 |
| DOI | 10.1021/acs.jmedchem.9b01252 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2989919114 |
| PMID | 31769984 |
| Type | article |
| Year | 2019 |

## Paper authors

- [Yong Ai](https://scholariq.org/researchers/yong-ai/)

## Paper primary topic

- [Wnt/β-catenin signaling in development and cancer](https://scholariq.org/topics/wnt-catenin-signaling-in-development-and-cancer/)

## Paper topics

- [Wnt/β-catenin signaling in development and cancer](https://scholariq.org/topics/wnt-catenin-signaling-in-development-and-cancer/)
- [Toxin Mechanisms and Immunotoxins](https://scholariq.org/topics/toxin-mechanisms-and-immunotoxins/)
- [Cancer Mechanisms and Therapy](https://scholariq.org/topics/cancer-mechanisms-and-therapy/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.