# Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/pyruvate-carboxylation-enables-growth-of-sdh-deficient-cells-by-supporting/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Simone Cardaci,Liang Zheng,Gillian Mackay,Niels J. F. van den Broek,Elaine D. MacKenzie,Colin Nixon,David Stevenson,Sergey Tumanov,Vinay Bulusu,Jurre J. Kamphorst,Alexei Vázquez,Stewart Fleming,Francesca Schiavi,Gabriela Kalna,Karen Blyth,Douglas Strathdee,Eyal Gottlieb |
| Citations | 291 |
| DOI | 10.1038/ncb3233 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/4591470 |
| OpenAlex ID | https://openalex.org/W1483430612 |
| PMID | 26302408 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Stewart Fleming](https://scholariq.org/researchers/stewart-fleming/)

## Paper primary topic

- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)

## Paper topics

- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)
- [Mitochondrial Function and Pathology](https://scholariq.org/topics/mitochondrial-function-and-pathology/)
- [Diet and metabolism studies](https://scholariq.org/topics/diet-and-metabolism-studies/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.