# Q493K and Q498H substitutions in Spike promote adaptation of SARS-CoV-2 in mice

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/q493k-and-q498h-substitutions-in-spike-promote-adaptation-of-sars-cov-2-in-mice/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Kun Huang,Yufei Zhang,Xianfeng Hui,Ya Zhao,Wenxiao Gong,Ting Wang,Shaoran Zhang,Yong Yang,Fēi Dèng,Qiang Zhang,Xi Chen,Ying Yang,Xiaomei Sun,Huanchun Chen,Yizhi Jane Tao,Zhong Zou,Meilin Jin |
| Citations | 143 |
| DOI | 10.1016/j.ebiom.2021.103381 |
| Fields | Medicine |
| Open Access | true |
| OA Status | gold |
| OA URL | http://www.thelancet.com/article/S2352396421001742/pdf |
| OpenAlex ID | https://openalex.org/W3162133013 |
| PMID | 33993052 |
| Type | article |
| Year | 2021 |

## Paper authors

- [Yufei Zhang](https://scholariq.org/researchers/yufei-zhang/)

## Paper journal

- [EBioMedicine](https://scholariq.org/journals/ebiomedicine/)

## Paper primary topic

- [SARS-CoV-2 and COVID-19 Research](https://scholariq.org/topics/sars-cov-2-and-covid-19-research/)

## Paper topics

- [SARS-CoV-2 and COVID-19 Research](https://scholariq.org/topics/sars-cov-2-and-covid-19-research/)
- [COVID-19 Clinical Research Studies](https://scholariq.org/topics/covid-19-clinical-research-studies/)
- [Long-Term Effects of COVID-19](https://scholariq.org/topics/long-term-effects-of-covid-19/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.