# Randomized Phase III Placebo-Controlled Trial of Letrozole Plus Oral Temsirolimus As First-Line Endocrine Therapy in Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/randomized-phase-iii-placebo-controlled-trial-of-letrozole-plus-oral/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Antonio C. Wolff,Ann Lazar,Igor Bondarenko,August Garin,Stephen Brincat,Louis W.C. Chow,Yan Sun,Zora Nešković‐Konstantinović,Rodrigo C. Guimarães,P. Fumoleau,Arlene Chan,Soulef Hachemi,Andrew Strahs,Maria Cincotta,Anna Berkenblit,Mizue Krygowski,Lih Lisa Kang,Laurence Moore,Daniel F. Hayes |
| Citations | 273 |
| DOI | 10.1200/jco.2011.38.3331 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2011.38.3331?role=tab |
| OpenAlex ID | https://openalex.org/W1990883066 |
| PMID | 23233719 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Laurence Moore](https://scholariq.org/researchers/laurence-moore/)
- [Ann Lazar](https://scholariq.org/researchers/ann-lazar/)

## Paper journal

- [Journal of Clinical Oncology](https://scholariq.org/journals/journal-of-clinical-oncology/)

## Paper primary topic

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

## Paper topics

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Estrogen and related hormone effects](https://scholariq.org/topics/estrogen-and-related-hormone-effects/)
- [Advanced Breast Cancer Therapies](https://scholariq.org/topics/advanced-breast-cancer-therapies/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.