# Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/reactivation-of-erk-signaling-causes-resistance-to-egfr-kinase-inhibitors/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Dalia Ercan,Chunxiao Xu,Masahiko Yanagita,Calixte S. Monast,Christine A. Pratilas,Joan Montero,Mohit Butaney,Takeshi Shimamura,Lynette M. Sholl,Elena V. Ivanova,Madhavi Tadi,Andrew M. Rogers,Claire E. Repellin,Marzia Capelletti,Ophélia Maertens,Eva M. Goetz,Anthony Letai,Levi A. Garraway,Matthew J. Lazzara,Neal Rosen,Nathanael S. Gray,Kwok‐Kin Wong,Pasi A. Jänne |
| Citations | 295 |
| DOI | 10.1158/2159-8290.cd-12-0103 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://cancerdiscovery.aacrjournals.org/content/candisc/2/10/934.full.pdf |
| OpenAlex ID | https://openalex.org/W2169460814 |
| PMID | 22961667 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Lynette M. Sholl](https://scholariq.org/researchers/lynette-m-sholl/)
- [Christine A. Pratilas](https://scholariq.org/researchers/christine-a-pratilas/)
- [Pasi A. Jänne](https://scholariq.org/researchers/pasi-a-janne/)

## Paper journal

- [Cancer Discovery](https://scholariq.org/journals/cancer-discovery/)

## Paper primary topic

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

## Paper topics

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)
- [Cancer therapeutics and mechanisms](https://scholariq.org/topics/cancer-therapeutics-and-mechanisms/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.