# Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/relief-of-profound-feedback-inhibition-of-mitogenic-signaling-by-raf-inhibitors/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Piro Lito,Christine A. Pratilas,Eric W. Joseph,Madhavi Tadi,Ensar Halilovic,Matthew Zubrowski,Alan Huang,Wai Lin Wong,Margaret K. Callahan,Taha Merghoub,Jedd D. Wolchok,Elisa de Stanchina,Sarat Chandarlapaty,Poulikos I. Poulikakos,James A. Fagin,Neal Rosen |
| Citations | 572 |
| DOI | 10.1016/j.ccr.2012.10.009 |
| Fields | Biochemistry, Genetics and Molecular Biology,Computer Science,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | http://www.cell.com/article/S1535610812004400/pdf |
| OpenAlex ID | https://openalex.org/W2041255253 |
| PMID | 23153539 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Christine A. Pratilas](https://scholariq.org/researchers/christine-a-pratilas/)

## Paper primary topic

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)

## Paper topics

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)
- [Computational Drug Discovery Methods](https://scholariq.org/topics/computational-drug-discovery-methods/)
- [HER2/EGFR in Cancer Research](https://scholariq.org/topics/her2-egfr-in-cancer-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.