# Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-finding portion of a phase 1/2 study

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/safety-and-activity-of-alectinib-against-systemic-disease-and-brain-metastases/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Shirish M. Gadgeel,Leena Gandhi,Gregory J. Riely,Alberto Chiappori,Howard West,Michele C. Azada,Peter N. Morcos,Ruey-min Lee,Linta Garcia,Li Yu,Frédéric Boisserie,Laura Di Laurenzio,Sophie Golding,Jotaro Sato,Shumpei Yokoyama,Tomohiro Tanaka,Sai‐Hong Ignatius Ou |
| Citations | 696 |
| DOI | 10.1016/s1470-2045(14)70362-6 |
| Fields | Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2010619956 |
| PMID | 25153538 |
| Type | article |
| Year | 2014 |

## Paper authors

- [Gregory J. Riely](https://scholariq.org/researchers/gregory-j-riely/)
- [Alberto Chiappori](https://scholariq.org/researchers/alberto-chiappori/)

## Paper journal

- [The Lancet Oncology](https://scholariq.org/journals/the-lancet-oncology/)

## Paper primary topic

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

## Paper topics

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [Lung Cancer Diagnosis and Treatment](https://scholariq.org/topics/lung-cancer-diagnosis-and-treatment/)
- [Lung Cancer Research Studies](https://scholariq.org/topics/lung-cancer-research-studies/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.