# Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/safety-and-efficacy-of-eculizumab-in-anti-acetylcholine-receptor-antibody/

## Facts

| Field | Value |
| --- | --- |
| Author Names | James F. Howard,Kimiaki Utsugisawa,Michael Benatar,Hiroyuki Murai,Richard J. Barohn,Isabel Illa,Saiju Jacob,John Vissing,Ted M. Burns,John T. Kissel,Srikanth Muppidi,Richard J. Nowak,Fanny O’Brien,Jingjing Wang,Renato Mantegazza,Claudio Mazia,Miguel Wilken,Carolina Ortea,Juliet Saba,Marcelo Rugiero,Mariela Bettini,Gonzalo Vidal,Alejandra Dalila Garcia,Phillipa J. Lamont,Wai-Kuen Leong,Heidi Boterhoven,Beverly Fyfe,L. Jackson Roberts,Mahi Jasinarachchi,Natasha Willlems,Julia Wanschitz,Wolfgang N. Löscher,Jan De Bleecker,Guy Van den Abeele,Kathy de Koning,Katrien De Mey,Rudy Mercelis,Linda Wagemaekers,Délphine Mahieu,Philip Van Damme,Charlotte Smetcoren,Olivier Stevens,Sarah Verjans,Ann D’Hondt,Petra Tilkin,Alzira Alves de Siqueira Carvalho,Rosa Hasan,Igor Dias Brockhausen,David Feder,Daniel Ambrosio,Ana Paula Souto Melo,Rosana Rocha,Bruno Bezerra Rosa,Thabata Veiga,Luiz Augusto da Silva,Jordana Gonçalves Geraldo,Maria da Penha Morita Ananias,Érica Nogueira Coelho,Gabriel Pina Paiva,M Tovar Pozo,Natália Prando,Debora Dada Martineli Torres,Cristiani Fernanda Butinhao,Érica Nogueira Coelho,Luciana Renata Cubas Volpe,Gustavo Duran,Tamires Cristina Gomes da Silva,Luiz Otavio Maia Gonçalves,Lucas Eduardo Pazetto,Luciana Souza Duca,Tomás Augusto Suriane Fialho,Maurício Friedrich,Alexandre Guerreiro,Henrique Mohr,Maurer Pereira Martins,Daiane da Cruz Pacheco,Ana Paula Macagnan,Aline de Cassia Santos,Acary Souza Bullé Oliveira,Ana Carolina Amaral de Andrade,Marcelo Annes,Valéria Cavalcante Lino,Wladimir Bocca Vieira de Rezende Pinto,Carolina Miranda,Fernanda Carrara,Iandra Souza,Angela Genge,Rami Massie,Natasha Campbell,Vera Bril,Hans Katzberg,Mehran Soltani,Eduardo Ng,Zaeem A. Siddiqi,Celile Phan,Derrick Blackmore,Stanislav Voháňka,Josef Bednařík,Magda Chmelikova,Marek Čierny |
| Citations | 816 |
| DOI | 10.1016/s1474-4422(17)30369-1 |
| Fields | Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2766784006 |
| PMID | 29066163 |
| Type | article |
| Year | 2017 |

## Paper authors

- [Hiroyuki Murai](https://scholariq.org/researchers/hiroyuki-murai/)
- [Jan De Bleecker](https://scholariq.org/researchers/jan-de-bleecker/)
- [L. Jackson Roberts](https://scholariq.org/researchers/l-jackson-roberts/)

## Paper primary topic

- [Myasthenia Gravis and Thymoma](https://scholariq.org/topics/myasthenia-gravis-and-thymoma/)

## Paper topics

- [Myasthenia Gravis and Thymoma](https://scholariq.org/topics/myasthenia-gravis-and-thymoma/)
- [Peripheral Neuropathies and Disorders](https://scholariq.org/topics/peripheral-neuropathies-and-disorders/)
- [Adrenal Hormones and Disorders](https://scholariq.org/topics/adrenal-hormones-and-disorders/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.