# Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/safety-pharmacokinetics-and-preliminary-assessment-of-efficacy-of-mecasermin/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Omar Khwaja,Eugenia Ho,Katherine V. Barnes,Heather M. O’Leary,Luis M. Pereira,Yaron Finkelstein,Charles A. Nelson,Vanessa Vogel‐Farley,Geneva DeGregorio,Ingrid A. Holm,Umakanth Khatwa,Kush Kapur,Mark E. Alexander,Deirdre M. Finnegan,Nicole G. Cantwell,Alexandra C. Walco,Leonard Rappaport,Matt Gregas,Raina N. Fichorova,Michael W. Shannon,Mriganka Sur,Walter E. Kaufmann |
| Citations | 213 |
| DOI | 10.1073/pnas.1311141111 |
| Fields | Biochemistry, Genetics and Molecular Biology,Neuroscience |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://www.pnas.org/content/pnas/111/12/4596.full.pdf |
| OpenAlex ID | https://openalex.org/W2109555365 |
| PMID | 24623853 |
| Type | article |
| Year | 2014 |

## Paper authors

- [Yaron Finkelstein](https://scholariq.org/researchers/yaron-finkelstein/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [Genetics and Neurodevelopmental Disorders](https://scholariq.org/topics/genetics-and-neurodevelopmental-disorders/)

## Paper topics

- [Genetics and Neurodevelopmental Disorders](https://scholariq.org/topics/genetics-and-neurodevelopmental-disorders/)
- [RNA modifications and cancer](https://scholariq.org/topics/rna-modifications-and-cancer/)
- [Autism Spectrum Disorder Research](https://scholariq.org/topics/autism-spectrum-disorder-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.