# Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/siponimod-versus-placebo-in-secondary-progressive-multiple-sclerosis-expand-a/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Ludwig Kappos,Amit Bar‐Or,Bruce Cree,Robert J. Fox,Gavin Giovannoni,Ralf Gold,Patrick Vermersch,Douglas L. Arnold,Sophie Arnould,Tatiana Scherz,Christian Wolf,Erik Wallström,Frank Dahlke,Anat Achiron,Lutz Achtnichts,Kadriye Ağan,Gülşen Akman‐Demir,Alison Allen,Jack P. Antel,Alfredo Rodríguez Antigüedad,Michelle Apperson,Angela Applebee,Guillermo Izquierdo Ayuso,Masayuki Baba,Ovidiu Băjenaru,Rodica Balasa,Belgin Petek Balcı,Michael Barnett,Ann Bass,V. Becker,Mihaela Bejinariu,Florian Then Bergh,Arnfin Bergmann,Evanthia Bernitsas,Achim Berthele,Virender Bhan,Felix Bischof,Randall J. Bjork,Gregg Blevins,Matthias Boehringer,Thomas Boerner,Robert Bonek,James D. Bowen,Allen C. Bowling,Alexey Boyко,Cavit Boz,Vera Bracknies,Stefan Braune,Vincenzo Brescia Morra,Bruno Brochet,Waldemar Brola,Paul Brownstone,M Brozman,Donald Brunet,Ioan Buraga,Margaret Burnett,Mathias Buttmann,Helmut Butzkueven,Jonathan Cahill,Jonathan Calkwood,William Camu,Mark Cascione,G. Castelnovo,Diego Centonze,João Cerqueira,Andrew Chan,Andrea Cimprichová,Stanley Cohan,Giancarlo Comi,Jill Ker Conway,Joanna A. Cooper,John R. Corboy,Jorge Correale,Brian Costell,David A. Cottrell,Patricia K. Coyle,Matthew Craner,Liying Cui,Luı́s Cunha,Anna Członkowska,Ana Silva,Joao de,de Sèze,Marc Debouverie,Jan Debruyne,D. Decoo,G. Defer,Tobias Derfuß,Norma Deri,Bhupesh Dihenia,Péter Diószeghy,Vladimír Donáth,Bénédicte Dubois,Martin Duddy,Pierre Duquette,Gilles Edan,Hüsnü Efendi,Stanton B. Elias,Peter Emrich,Bonaventura Casanova Estruch |
| Citations | 932 |
| DOI | 10.1016/s0140-6736(18)30475-6 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2790816436 |
| PMID | 29576505 |
| Type | article |
| Year | 2018 |

## Paper authors

- [Diego Centonze](https://scholariq.org/researchers/diego-centonze/)
- [Caroline Papeix](https://scholariq.org/researchers/caroline-papeix/)

## Paper journal

- [The Lancet](https://scholariq.org/journals/the-lancet/)

## Paper primary topic

- [Multiple Sclerosis Research Studies](https://scholariq.org/topics/multiple-sclerosis-research-studies/)

## Paper topics

- [Multiple Sclerosis Research Studies](https://scholariq.org/topics/multiple-sclerosis-research-studies/)
- [Sphingolipid Metabolism and Signaling](https://scholariq.org/topics/sphingolipid-metabolism-and-signaling/)
- [Spondyloarthritis Studies and Treatments](https://scholariq.org/topics/spondyloarthritis-studies-and-treatments/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.