# Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/structure-based-design-of-irreversible-human-kat-ii-inhibitors-discovery-of-new/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jamison B. Tuttle,Marie Anderson,Bruce M. Bechle,Brian Campbell,Cheng Chang,Amy B. Dounay,Edelweiss Evrard,Kari R. Fonseca,Xinmin Gan,Somraj Ghosh,W. Elliott Horner,Larry C. James,Jiyoung Kim,Laura A. McAllister,Jayvardhan Pandit,Vinod D. Parikh,Brian Rago,Michelle A. Salafia,Christine A. Strick,Laura E. Zawadzke,Patrick R. Verhoest |
| Citations | 25 |
| DOI | 10.1021/ml300237v |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine,Neuroscience |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q2kh0pnv |
| OpenAlex ID | https://openalex.org/W2034000656 |
| PMID | 24900560 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Somraj Ghosh](https://scholariq.org/researchers/somraj-ghosh/)

## Paper primary topic

- [Tryptophan and brain disorders](https://scholariq.org/topics/tryptophan-and-brain-disorders/)

## Paper topics

- [Tryptophan and brain disorders](https://scholariq.org/topics/tryptophan-and-brain-disorders/)
- [Bipolar Disorder and Treatment](https://scholariq.org/topics/bipolar-disorder-and-treatment/)
- [Pharmacological Receptor Mechanisms and Effects](https://scholariq.org/topics/pharmacological-receptor-mechanisms-and-effects/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.