# <sup>V600E</sup> BRAF is associated with disabled feedback inhibition of RAF–MEK signaling and elevated transcriptional output of the pathway

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/sup-v600e-sup-braf-is-associated-with-disabled-feedback-inhibition-of-raf-mek/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Christine A. Pratilas,Barry S. Taylor,Qing Ye,Agnès Viale,Chris Sander,David B. Solit,Neal Rosen |
| Citations | 617 |
| DOI | 10.1073/pnas.0900780106 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://www.pnas.org/doi/pdf/10.1073/pnas.0900780106 |
| OpenAlex ID | https://openalex.org/W2038683568 |
| PMID | 19251651 |
| Type | article |
| Year | 2009 |

## Paper authors

- [Christine A. Pratilas](https://scholariq.org/researchers/christine-a-pratilas/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)

## Paper topics

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)
- [Protein Tyrosine Phosphatases](https://scholariq.org/topics/protein-tyrosine-phosphatases/)
- [Protein Kinase Regulation and GTPase Signaling](https://scholariq.org/topics/protein-kinase-regulation-and-gtpase-signaling/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.