# Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike–ACE2 Interaction

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/synthetic-heparan-sulfate-mimetic-pixatimod-pg545-potently-inhibits-sars-cov-2/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Scott E. Guimond,Courtney J. Mycroft‐West,Neha S. Gandhi,Julia A. Tree,Thuy T. Le,C. Mirella Spalluto,María Victoria Humbert,Karen R. Buttigieg,Naomi S. Coombes,Michael J. Elmore,Matthew E. Wand,Kristina Nystrôm,Joanna Said,Yin Xiang Setoh,Alberto A. Amarilla,Naphak Modhiran,Julian D. J. Sng,Mohit Chhabra,Paul R. Young,Daniel J. Rawle,Marcelo A. Lima,Edwin A. Yates,Richard Karlsson,Rebecca L. Miller,Yen‐Hsi Chen,Ieva Bagdonaite,Zhang Yang,James P. Stewart,Dung Nguyen,Stephen M. Laidlaw,Edward Hammond,Keith Dredge,Tom Wilkinson,Daniel Watterson,Alexander A. Khromykh,Andreas Suhrbier,Miles W. Carroll,Edward Trybala,Tomas Bergström,Vito Ferro,Mark A. Skidmore,Jeremy E. Turnbull |
| Citations | 112 |
| DOI | 10.1021/acscentsci.1c01293 |
| Fields | Medicine |
| Open Access | true |
| OA Status | diamond |
| OA URL | https://doi.org/10.1021/acscentsci.1c01293 |
| OpenAlex ID | https://openalex.org/W4226483144 |
| PMID | 35647275 |
| Type | article |
| Year | 2022 |

## Paper authors

- [Matthew E. Wand](https://scholariq.org/researchers/matthew-e-wand/)

## Paper primary topic

- [SARS-CoV-2 and COVID-19 Research](https://scholariq.org/topics/sars-cov-2-and-covid-19-research/)

## Paper topics

- [SARS-CoV-2 and COVID-19 Research](https://scholariq.org/topics/sars-cov-2-and-covid-19-research/)
- [Respiratory viral infections research](https://scholariq.org/topics/respiratory-viral-infections-research/)
- [Lung Cancer Research Studies](https://scholariq.org/topics/lung-cancer-research-studies/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.