# Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/systemic-biosynthesis-of-prostacyclin-by-cyclooxygenase-cox-2-the-human/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Brendan McAdam,Francesca Catella-Lawson,Issam A. Mardini,Shiv Kapoor,John A. Lawson,Garret A. FitzGerald |
| Citations | 1,311 |
| DOI | 10.1073/pnas.96.1.272 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OpenAlex ID | https://openalex.org/W2020563114 |
| PMID | 9874808 |
| Type | article |
| Year | 1999 |

## Paper authors

- [Garret A. FitzGerald](https://scholariq.org/researchers/garret-a-fitzgerald/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [Inflammatory mediators and NSAID effects](https://scholariq.org/topics/inflammatory-mediators-and-nsaid-effects/)

## Paper topics

- [Inflammatory mediators and NSAID effects](https://scholariq.org/topics/inflammatory-mediators-and-nsaid-effects/)
- [Estrogen and related hormone effects](https://scholariq.org/topics/estrogen-and-related-hormone-effects/)
- [Eicosanoids and Hypertension Pharmacology](https://scholariq.org/topics/eicosanoids-and-hypertension-pharmacology/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.