# Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/targeting-chk1-in-p53-deficient-triple-negative-breast-cancer-is-therapeutically/

## Facts

| Field | Value |
| --- | --- |
| Author Names | X. Cynthia,Shirong Cai,Shunqiang Li,Christine E. Ryan,Zhanfang Guo,W. Timothy Schaiff,Lin Li,Jeremy Hoog,Reece Goiffon,Aleix Prat,Rebecca Aft,Matthew J. Ellis,Helen Piwnica‐Worms |
| Citations | 224 |
| DOI | 10.1172/jci58765 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://digitalcommons.wustl.edu/cgi/viewcontent.cgi?article=2693&context=open_access_pubs |
| OpenAlex ID | https://openalex.org/W2072544833 |
| PMID | 22446188 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Christine E. Ryan](https://scholariq.org/researchers/christine-e-ryan/)

## Paper primary topic

- [Cancer-related Molecular Pathways](https://scholariq.org/topics/cancer-related-molecular-pathways/)

## Paper topics

- [Cancer-related Molecular Pathways](https://scholariq.org/topics/cancer-related-molecular-pathways/)
- [DNA Repair Mechanisms](https://scholariq.org/topics/dna-repair-mechanisms/)
- [Microtubule and mitosis dynamics](https://scholariq.org/topics/microtubule-and-mitosis-dynamics/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.