# TET2 regulates early and late transitions in exhausted CD8 <sup>+</sup> T cell differentiation and limits CAR T cell function

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/tet2-regulates-early-and-late-transitions-in-exhausted-cd8-sup-sup-t-cell/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Alexander J. Dimitri,Amy E. Baxter,Gregory M. Chen,Caitlin R. Hopkins,Geoffrey T. Rouin,Hua Huang,Weimin Kong,Christopher Holliday,Volker Wiebking,Robert L. Bartoszek,Sydney Drury,Katherine Tuite-Dalton,Owen Koucky,Zeyu Chen,Josephine R. Giles,Alexander T. Dils,In-Young Jung,Roddy S. O’Connor,Sierra M. Collins,J.K. Everett,Kevin R. Amses,Scott Sherrill-Mix,Aditi Chandra,Naomi Goldman,Golnaz Vahedi,Julie K. Jadlowsky,Regina M. Young,J. Joseph Melenhorst,Shannon L. Maude,Bruce L. Levine,Noelle V. Frey,Shelley L. Berger,Stephan A. Grupp,David L. Porter,Friederike Herbst,Matthew H. Porteus,Shannon A. Carty,Frederic D. Bushman,Evan W. Weber,E. John Wherry,Martha S. Jordan,Joseph A. Fraietta |
| Citations | 30 |
| DOI | 10.1126/sciadv.adp9371 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | gold |
| OA URL | https://www.science.org/doi/pdf/10.1126/sciadv.adp9371?download=true |
| OpenAlex ID | https://openalex.org/W4404307185 |
| PMID | 39536093 |
| Type | article |
| Year | 2024 |

## Paper authors

- [David L. Porter](https://scholariq.org/researchers/david-l-porter/)

## Paper primary topic

- [CAR-T cell therapy research](https://scholariq.org/topics/car-t-cell-therapy-research/)

## Paper topics

- [CAR-T cell therapy research](https://scholariq.org/topics/car-t-cell-therapy-research/)
- [Immune Cell Function and Interaction](https://scholariq.org/topics/immune-cell-function-and-interaction/)
- [Virus-based gene therapy research](https://scholariq.org/topics/virus-based-gene-therapy-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.