# The Antiproliferative Effect of Sildenafil on Pulmonary Artery Smooth Muscle Cells Is Mediated via Upregulation of Mitogen-Activated Protein Kinase Phosphatase-1 and Degradation of Extracellular Signal-Regulated Kinase 1/2 Phosphorylation

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/the-antiproliferative-effect-of-sildenafil-on-pulmonary-artery-smooth-muscle/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Bingbing Li,Ling-Chao Yang,Jianying Shen,Chunshen Wang,Zhen Jiang |
| Citations | 41 |
| DOI | 10.1213/01.ane.0000278736.81133.26 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2017206871 |
| PMID | 17898384 |
| Type | article |
| Year | 2007 |

## Paper authors

- [Ling-Chao Yang](https://scholariq.org/researchers/ling-chao-yang/)

## Paper journal

- [Anesthesia & Analgesia](https://scholariq.org/journals/anesthesia-and-analgesia/)

## Paper primary topic

- [Phosphodiesterase function and regulation](https://scholariq.org/topics/phosphodiesterase-function-and-regulation/)

## Paper topics

- [Phosphodiesterase function and regulation](https://scholariq.org/topics/phosphodiesterase-function-and-regulation/)
- [Pulmonary Hypertension Research and Treatments](https://scholariq.org/topics/pulmonary-hypertension-research-and-treatments/)
- [Nitric Oxide and Endothelin Effects](https://scholariq.org/topics/nitric-oxide-and-endothelin-effects/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.