# The cAMP phosphodiesterase-4D7 (PDE4D7) is downregulated in androgen-independent prostate cancer cells and mediates proliferation by compartmentalising cAMP at the plasma membrane of VCaP prostate cancer cells

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/the-camp-phosphodiesterase-4d7-pde4d7-is-downregulated-in-androgen-independent/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Deborah J. Henderson,Anne-Marie Byrne,Kalyan Dulla,Guido Jenster,Ralf Hoffmann,George S. Baillie,Miles D. Houslay |
| Citations | 49 |
| DOI | 10.1038/bjc.2014.22 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://www.nature.com/articles/bjc201422.pdf |
| OpenAlex ID | https://openalex.org/W1971283086 |
| PMID | 24518597 |
| Type | article |
| Year | 2014 |

## Paper authors

- [Ralf Hoffmann](https://scholariq.org/researchers/ralf-hoffmann/)

## Paper journal

- [British Journal of Cancer](https://scholariq.org/journals/british-journal-of-cancer/)

## Paper primary topic

- [Phosphodiesterase function and regulation](https://scholariq.org/topics/phosphodiesterase-function-and-regulation/)

## Paper topics

- [Phosphodiesterase function and regulation](https://scholariq.org/topics/phosphodiesterase-function-and-regulation/)
- [Histone Deacetylase Inhibitors Research](https://scholariq.org/topics/histone-deacetylase-inhibitors-research/)
- [Protein Kinase Regulation and GTPase Signaling](https://scholariq.org/topics/protein-kinase-regulation-and-gtpase-signaling/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
