# The mechanism of acquired resistance to irreversible EGFR tyrosine kinase inhibitor-afatinib in lung adenocarcinoma patients

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/the-mechanism-of-acquired-resistance-to-irreversible-egfr-tyrosine-kinase/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Shang‐Gin Wu,Yinan Liu,Meng‐Feng Tsai,Yih‐Leong Chang,Chong‐Jen Yu,Pan‐Chyr Yang,James Chih‐Hsin Yang,Yueh‐Feng Wen,Jin‐Yuan Shih |
| Citations | 237 |
| DOI | 10.18632/oncotarget.7189 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | diamond |
| OA URL | http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=7189&path%5B%5D=20490 |
| OpenAlex ID | https://openalex.org/W2292347930 |
| PMID | 26862733 |
| Type | article |
| Year | 2016 |

## Paper authors

- [Shang‐Gin Wu](https://scholariq.org/researchers/shang-gin-wu/)
- [Yih‐Leong Chang](https://scholariq.org/researchers/yih-leong-chang/)
- [Yinan Liu](https://scholariq.org/researchers/yinan-liu/)
- [Chong‐Jen Yu](https://scholariq.org/researchers/chong-jen-yu/)
- [James Chih‐Hsin Yang](https://scholariq.org/researchers/james-chih-hsin-yang/)
- [Jin‐Yuan Shih](https://scholariq.org/researchers/jin-yuan-shih/)

## Paper journal

- [Oncotarget](https://scholariq.org/journals/oncotarget/)

## Paper primary topic

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

## Paper topics

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)
- [Fibroblast Growth Factor Research](https://scholariq.org/topics/fibroblast-growth-factor-research/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.