# The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/the-mtor-pathway-is-regulated-by-polycystin-1-and-its-inhibition-reverses-renal/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jonathan M. Shillingford,Noel Murcia,Claire H. Larson,Seng Hui Low,Ryan C. Hedgepeth,Nicole Brown,Chris A. Flask,Andrew C. Novick,David A. Goldfarb,Albrecht Kramer-Zucker,Gerd Walz,Klaus Piontek,Gregory G. Germino,Thomas Weimbs |
| Citations | 800 |
| DOI | 10.1073/pnas.0509694103 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://www.pnas.org/content/pnas/103/14/5466.full.pdf |
| OpenAlex ID | https://openalex.org/W2141331673 |
| PMID | 16567633 |
| Type | article |
| Year | 2006 |

## Paper authors

- [Jonathan M. Shillingford](https://scholariq.org/researchers/jonathan-m-shillingford/)
- [Gerd Walz](https://scholariq.org/researchers/gerd-walz/)
- [Thomas Weimbs](https://scholariq.org/researchers/thomas-weimbs/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [Genetic and Kidney Cyst Diseases](https://scholariq.org/topics/genetic-and-kidney-cyst-diseases/)

## Paper topics

- [Genetic and Kidney Cyst Diseases](https://scholariq.org/topics/genetic-and-kidney-cyst-diseases/)
- [Biomedical Research and Pathophysiology](https://scholariq.org/topics/biomedical-research-and-pathophysiology/)
- [Renal and related cancers](https://scholariq.org/topics/renal-and-related-cancers/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.