# The novel methoxetamine analogs N-ethylnorketamine hydrochloride (NENK), 2-MeO-N-ethylketamine hydrochloride (2-MeO-NEK), and 4-MeO-N-ethylketamine hydrochloride (4-MeO-NEK) elicit rapid antidepressant effects via activation of AMPA and 5-HT2 receptors

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/the-novel-methoxetamine-analogs-n-ethylnorketamine-hydrochloride-nenk-2-meo-n/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Leandro Val Sayson,Chrislean Jun Botanas,Raly James Perez Custodio,Arvie Abiero,Mikyung Kim,Hyun Jun Lee,Hee Jin Kim,Sung Yeun Yoo,Kun Won Lee,Hye Won Ryu,Srijan Acharya,Kyeong‐Man Kim,Yong Sup Lee,Jae Hoon Cheong |
| Citations | 19 |
| DOI | 10.1007/s00213-019-05219-x |
| Fields | Medicine,Neuroscience,Pharmacology, Toxicology and Pharmaceutics |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2925171307 |
| PMID | 30891619 |
| Type | article |
| Year | 2019 |

## Paper authors

- [Hye Won Ryu](https://scholariq.org/researchers/hye-won-ryu/)

## Paper journal

- [Psychopharmacology](https://scholariq.org/journals/psychopharmacology/)

## Paper primary topic

- [Treatment of Major Depression](https://scholariq.org/topics/treatment-of-major-depression/)

## Paper topics

- [Treatment of Major Depression](https://scholariq.org/topics/treatment-of-major-depression/)
- [Neurotransmitter Receptor Influence on Behavior](https://scholariq.org/topics/neurotransmitter-receptor-influence-on-behavior/)
- [Forensic Toxicology and Drug Analysis](https://scholariq.org/topics/forensic-toxicology-and-drug-analysis/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.