# The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/the-raf-inhibitor-plx4032-inhibits-erk-signaling-and-tumor-cell-proliferation-in/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Eric W. Joseph,Christine A. Pratilas,Poulikos I. Poulikakos,Madhavi Tadi,Weiqing Wang,Barry S. Taylor,Ensar Halilovic,Yogindra Persaud,Feng Xing,Agnès Viale,James Tsai,Paul B. Chapman,Gideon Bollag,David B. Solit,Neal Rosen |
| Citations | 448 |
| DOI | 10.1073/pnas.1008990107 |
| Fields | Biochemistry, Genetics and Molecular Biology,Computer Science,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/2930420 |
| OpenAlex ID | https://openalex.org/W1982972087 |
| PMID | 20668238 |
| Type | article |
| Year | 2010 |

## Paper authors

- [Christine A. Pratilas](https://scholariq.org/researchers/christine-a-pratilas/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)

## Paper topics

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)
- [Cytokine Signaling Pathways and Interactions](https://scholariq.org/topics/cytokine-signaling-pathways-and-interactions/)
- [Computational Drug Discovery Methods](https://scholariq.org/topics/computational-drug-discovery-methods/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.