# Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/thymidylate-synthase-gene-amplification-in-human-colon-cancer-cell-lines/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Sitki Copur,Keisuke Aiba,J C Drake,C J Allegra,Edward Chu |
| Citations | 181 |
| DOI | 10.1016/0006-2952(95)00067-a |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2065915399 |
| PMID | 7763285 |
| Type | article |
| Year | 1995 |

## Paper authors

- [Edward Chu](https://scholariq.org/researchers/edward-chu/)

## Paper journal

- [Biochemical Pharmacology](https://scholariq.org/journals/biochemical-pharmacology/)

## Paper primary topic

- [Colorectal Cancer Treatments and Studies](https://scholariq.org/topics/colorectal-cancer-treatments-and-studies/)

## Paper topics

- [Colorectal Cancer Treatments and Studies](https://scholariq.org/topics/colorectal-cancer-treatments-and-studies/)
- [Folate and B Vitamins Research](https://scholariq.org/topics/folate-and-b-vitamins-research/)
- [Biochemical and Molecular Research](https://scholariq.org/topics/biochemical-and-molecular-research/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.