# Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244)

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/transcriptional-pathway-signatures-predict-mek-addiction-and-response-to/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jonathan R. Dry,Sandra Pavey,Christine A. Pratilas,Chris Harbron,Sarah Runswick,Darren Hodgson,Christine M. Chresta,Rose McCormack,Natalie Byrne,Mark Cockerill,Alexander Graham,Garry Beran,Andrew Cassidy,Carolyn Haggerty,Helen Brown,Gillian Ellison,Judy Dering,Barry S. Taylor,Mitchell Stark,Vanessa Bonazzi,Sugandha Ravishankar,Leisl Packer,Feng Xing,David B. Solit,Richard S. Finn,Neal Rosen,Nicholas K. Hayward,Tim French,Paul D. Smith |
| Citations | 266 |
| DOI | 10.1158/0008-5472.can-09-1577 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://aacrjournals.org/cancerres/article-pdf/70/6/2264/2646598/2264.pdf |
| OpenAlex ID | https://openalex.org/W2128445526 |
| PMID | 20215513 |
| Type | article |
| Year | 2010 |

## Paper authors

- [Christine A. Pratilas](https://scholariq.org/researchers/christine-a-pratilas/)

## Paper journal

- [Cancer Research](https://scholariq.org/journals/cancer-research/)

## Paper primary topic

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)

## Paper topics

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)
- [Colorectal Cancer Treatments and Studies](https://scholariq.org/topics/colorectal-cancer-treatments-and-studies/)
- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.