# USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/usp22-promotes-hypoxia-induced-hepatocellular-carcinoma-stemness-by-a-hif1-usp22/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Sunbin Ling,Qiaonan Shan,Qifan Zhan,Qianwei Ye,Peng Liu,Shengjun Xu,Xin He,Jian Ma,Jiajia Xiang,Guangjiang Jiang,Xue Wen,Zijie Feng,Yuan Wu,Tingting Feng,Li Xu,Kangchen Chen,Xuanyu Zhang,Rongli Wei,Chenzhi Zhang,Beini Cen,Haiyang Xie,Penghong Song,Jimin Liu,Shusen Zheng,Xiao Xu |
| Citations | 232 |
| DOI | 10.1136/gutjnl-2019-319616 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2990971331 |
| PMID | 31776228 |
| Type | article |
| Year | 2019 |

## Paper authors

- [Xiao Xu](https://scholariq.org/researchers/xiao-xu/)

## Paper journal

- [Gut](https://scholariq.org/journals/gut/)

## Paper primary topic

- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)

## Paper topics

- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)
- [Cancer-related Molecular Pathways](https://scholariq.org/topics/cancer-related-molecular-pathways/)
- [Ubiquitin and proteasome pathways](https://scholariq.org/topics/ubiquitin-and-proteasome-pathways/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.