# Vepdegestrant, a PROTAC Estrogen Receptor Degrader, in Advanced Breast Cancer

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/vepdegestrant-a-protac-estrogen-receptor-degrader-in-advanced-breast-cancer/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Mario Campone,Michelino De Laurentiis,Komal Jhaveri,Xichun Hu,Sylvain Ladoire,Anne Patsouris,Claudio Zamagni,Jiuwei Cui,Marina Elena Cazzaniga,Timuçin Çil,Katarzyna J. Jerzak,C.S. Fuentes,Tetsuhiro Yoshinami,Álvaro Rodríguez-Lescure,Ahmet Sezer,Andrea Fontana,Valentina Guarneri,Andrea Molckovsky,Marie‐Ange Mouret‐Reynier,Umut Demırcı,Yongqiang Zhang,Olga Valota,Dongrui R. Lu,Marcella Martignoni,Janaki Parameswaran,Xin Zhi,Erika Hamilton |
| Citations | 116 |
| DOI | 10.1056/nejmoa2505725 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W4410919567 |
| PMID | 40454645 |
| Type | article |
| Year | 2025 |

## Paper authors

- [Yongqiang Zhang](https://scholariq.org/researchers/yongqiang-zhang/)

## Paper journal

- [New England Journal of Medicine](https://scholariq.org/journals/new-england-journal-of-medicine/)

## Paper primary topic

- [Protein Degradation and Inhibitors](https://scholariq.org/topics/protein-degradation-and-inhibitors/)

## Paper topics

- [Protein Degradation and Inhibitors](https://scholariq.org/topics/protein-degradation-and-inhibitors/)
- [HER2/EGFR in Cancer Research](https://scholariq.org/topics/her2-egfr-in-cancer-research/)
- [Advanced Breast Cancer Therapies](https://scholariq.org/topics/advanced-breast-cancer-therapies/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.