# David E. Root

**Type:** Researchers  
**Canonical URL:** https://scholariq.org/researchers/david-e-root/

## Facts

| Field | Value |
| --- | --- |
| Citations | 71,810 |
| Field | CRISPR and Genetic Engineering |
| h-index | 106 |
| i10-index | 276 |
| Last Known Institution | Broad Institute |
| OpenAlex ID | https://openalex.org/A5086771961 |
| ORCID iD | https://orcid.org/0000-0001-5122-861X |
| Works | 809 |

## Researcher papers

- [Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1](https://scholariq.org/papers/systematic-rna-interference-reveals-that-oncogenic-kras-driven-cancers-require/)
- [Functional genomics reveal that the serine synthesis pathway is essential in breast cancer](https://scholariq.org/papers/functional-genomics-reveal-that-the-serine-synthesis-pathway-is-essential-in/)
- [The bromodomain protein Brd4 insulates chromatin from DNA damage signalling](https://scholariq.org/papers/the-bromodomain-protein-brd4-insulates-chromatin-from-dna-damage-signalling/)
- [DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia](https://scholariq.org/papers/dot1l-inhibits-sirt1-mediated-epigenetic-silencing-to-maintain-leukemic-gene/)
- [Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in <i>LKB1</i> -Mutant Lung Cancer](https://scholariq.org/papers/metabolic-and-functional-genomic-studies-identify-deoxythymidylate-kinase-as-a/)

## Researcher topics

- [CRISPR and Genetic Engineering](https://scholariq.org/topics/crispr-and-genetic-engineering/)
- [Protein Degradation and Inhibitors](https://scholariq.org/topics/protein-degradation-and-inhibitors/)
- [Cancer Genomics and Diagnostics](https://scholariq.org/topics/cancer-genomics-and-diagnostics/)
- [RNA modifications and cancer](https://scholariq.org/topics/rna-modifications-and-cancer/)
- [Radio Frequency Integrated Circuit Design](https://scholariq.org/topics/radio-frequency-integrated-circuit-design/)

## Researcher university

- [Broad Institute](https://scholariq.org/institutions/broad-institute/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.