# David M. Holtzman

**Type:** Researchers  
**Canonical URL:** https://scholariq.org/researchers/david-m-holtzman/

## Facts

| Field | Value |
| --- | --- |
| Citations | 173,539 |
| Field | Alzheimer's disease research and treatments |
| h-index | 208 |
| i10-index | 652 |
| Last Known Institution | Washington University in St. Louis |
| OpenAlex ID | https://openalex.org/A5088998527 |
| ORCID iD | https://orcid.org/0000-0002-3400-0856 |
| Works | 1,029 |

## Researcher papers

Showing 12 of 13.

- [The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease](https://scholariq.org/papers/the-diagnosis-of-mild-cognitive-impairment-due-to-alzheimer-s-disease/)
- [Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease](https://scholariq.org/papers/clinical-and-biomarker-changes-in-dominantly-inherited-alzheimer-s-disease/)
- [Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria](https://scholariq.org/papers/preclinical-alzheimer-s-disease-definition-natural-history-and-diagnostic/)
- [Amyloid-β Dynamics Are Regulated by Orexin and the Sleep-Wake Cycle](https://scholariq.org/papers/amyloid-dynamics-are-regulated-by-orexin-and-the-sleep-wake-cycle/)
- [Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums](https://scholariq.org/papers/brain-insulin-resistance-in-type-2-diabetes-and-alzheimer-disease-concepts-and/)
- [ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy](https://scholariq.org/papers/apoe4-markedly-exacerbates-tau-mediated-neurodegeneration-in-a-mouse-model-of/)
- [Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease](https://scholariq.org/papers/tau-and-a-imaging-csf-measures-and-cognition-in-alzheimer-s-disease/)
- [Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study](https://scholariq.org/papers/spatial-patterns-of-neuroimaging-biomarker-change-in-individuals-from-families/)
- [Loss of Intranetwork and Internetwork Resting State Functional Connections with Alzheimer's Disease Progression](https://scholariq.org/papers/loss-of-intranetwork-and-internetwork-resting-state-functional-connections-with/)
- [Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels](https://scholariq.org/papers/slow-wave-sleep-disruption-increases-cerebrospinal-fluid-amyloid-levels/)
- [The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers](https://scholariq.org/papers/the-alzheimer-s-association-external-quality-control-program-for-cerebrospinal/)
- [CSF biomarker variability in the Alzheimer's Association quality control program](https://scholariq.org/papers/csf-biomarker-variability-in-the-alzheimer-s-association-quality-control-program/)

## Researcher topics

- [Alzheimer's disease research and treatments](https://scholariq.org/topics/alzheimer-s-disease-research-and-treatments/)
- [Dementia and Cognitive Impairment Research](https://scholariq.org/topics/dementia-and-cognitive-impairment-research/)
- [Neuroinflammation and Neurodegeneration Mechanisms](https://scholariq.org/topics/neuroinflammation-and-neurodegeneration-mechanisms/)
- [Cholinesterase and Neurodegenerative Diseases](https://scholariq.org/topics/cholinesterase-and-neurodegenerative-diseases/)
- [Neuroscience and Neuropharmacology Research](https://scholariq.org/topics/neuroscience-and-neuropharmacology-research/)

## Researcher university

- [Washington University in St. Louis](https://scholariq.org/institutions/washington-university-in-st-louis/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.