# Frédéric Checler

**Type:** Researchers  
**Canonical URL:** https://scholariq.org/researchers/frederic-checler/

## Facts

| Field | Value |
| --- | --- |
| Citations | 22,548 |
| Field | Alzheimer's disease research and treatments |
| h-index | 76 |
| i10-index | 244 |
| Last Known Institution | Centre National de la Recherche Scientifique |
| OpenAlex ID | https://openalex.org/A5086409965 |
| ORCID iD | https://orcid.org/0000-0003-2098-1750 |
| Works | 426 |

## Researcher papers

- [Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP](https://scholariq.org/papers/presenilin-dependent-transcriptional-control-of-the-a-degrading-enzyme/)
- [Intracellular Aβ42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease](https://scholariq.org/papers/intracellular-a-42-activates-p53-promoter-a-pathway-to-neurodegeneration-in/)
- [Wild-type but Not Parkinson's Disease-related Ala-53 → Thr Mutant α-Synuclein Protects Neuronal Cells from Apoptotic Stimuli](https://scholariq.org/papers/wild-type-but-not-parkinson-s-disease-related-ala-53-thr-mutant-synuclein/)
- [Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease](https://scholariq.org/papers/transcriptional-repression-of-p53-by-parkin-and-impairment-by-mutations/)
- [New protease inhibitors prevent γ-secretase-mediated production of Aβ40/42 without affecting Notch cleavage](https://scholariq.org/papers/new-protease-inhibitors-prevent-secretase-mediated-production-of-a-40-42-without/)

## Researcher topics

- [Alzheimer's disease research and treatments](https://scholariq.org/topics/alzheimer-s-disease-research-and-treatments/)
- [Neuropeptides and Animal Physiology](https://scholariq.org/topics/neuropeptides-and-animal-physiology/)
- [Peptidase Inhibition and Analysis](https://scholariq.org/topics/peptidase-inhibition-and-analysis/)
- [Prion Diseases and Protein Misfolding](https://scholariq.org/topics/prion-diseases-and-protein-misfolding/)
- [Cholinesterase and Neurodegenerative Diseases](https://scholariq.org/topics/cholinesterase-and-neurodegenerative-diseases/)

## Researcher university

- [Centre National de la Recherche Scientifique](https://scholariq.org/institutions/centre-national-de-la-recherche-scientifique/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.