# Hirofumi Kai

**Type:** Researchers  
**Canonical URL:** https://scholariq.org/researchers/hirofumi-kai/

## Facts

| Field | Value |
| --- | --- |
| Citations | 6,842 |
| Field | Neonatal Respiratory Health Research |
| h-index | 42 |
| i10-index | 159 |
| Last Known Institution | Kumamoto University |
| OpenAlex ID | https://openalex.org/A5053776224 |
| ORCID iD | 0000-0001-9335-2424 |
| Works | 384 |

## Researcher papers

- [Gene Expression Profiling of Cells, Tissues, and Developmental Stages of the Nematode C. elegans](https://scholariq.org/papers/gene-expression-profiling-of-cells-tissues-and-developmental-stages-of-the/)
- [Activation of NF-κB by nontypeable <i>Hemophilus influenzae</i> is mediated by toll-like receptor 2-TAK1-dependent NIK–IKKα/β–IκBα and MKK3/6–p38 MAP kinase signaling pathways in epithelial cells](https://scholariq.org/papers/activation-of-nf-b-by-nontypeable-i-hemophilus-influenzae-i-is-mediated-by-toll/)
- [The Tumor Suppressor Cylindromatosis (CYLD) Acts as a Negative Regulator for Toll-like Receptor 2 Signaling via Negative Cross-talk with TRAF6 and TRAF7](https://scholariq.org/papers/the-tumor-suppressor-cylindromatosis-cyld-acts-as-a-negative-regulator-for-toll/)
- [MUC1 Mucin Is a Negative Regulator of Toll-Like Receptor Signaling](https://scholariq.org/papers/muc1-mucin-is-a-negative-regulator-of-toll-like-receptor-signaling/)
- [Glucocorticoids Synergistically Enhance NontypeableHaemophilus influenzae-induced Toll-like Receptor 2 Expression via a Negative Cross-talk with p38 MAP Kinase](https://scholariq.org/papers/glucocorticoids-synergistically-enhance-nontypeablehaemophilus-influenzae/)
- [Inhibition of p38 MAPK by Glucocorticoids via Induction of MAPK Phosphatase-1 Enhances Nontypeable Haemophilus influenzae-induced Expression of Toll-like Receptor 2](https://scholariq.org/papers/inhibition-of-p38-mapk-by-glucocorticoids-via-induction-of-mapk-phosphatase-1/)
- [Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M](https://scholariq.org/papers/glucocorticoids-suppress-inflammation-via-the-upregulation-of-negative-regulator/)
- [p53 Regulates Toll-Like Receptor 3 Expression and Function in Human Epithelial Cell Lines](https://scholariq.org/papers/p53-regulates-toll-like-receptor-3-expression-and-function-in-human-epithelial/)
- [Promoter hypomethylation of Toll‐like receptor‐2 gene is associated with increased proinflammatory response towardbacterial peptidoglycan in cystic fibrosis bronchial epithelial cells](https://scholariq.org/papers/promoter-hypomethylation-of-toll-like-receptor-2-gene-is-associated-with/)
- [Crystal structure of the IL-15–IL-15Rα complex, a cytokine-receptor unit presented in trans](https://scholariq.org/papers/crystal-structure-of-the-il-15-il-15r-complex-a-cytokine-receptor-unit-presented/)
- [Genetic background, recent advances in molecular biology, and development of novel therapy in Alport syndrome](https://scholariq.org/papers/genetic-background-recent-advances-in-molecular-biology-and-development-of-novel/)

## Researcher topics

- [Neonatal Respiratory Health Research](https://scholariq.org/topics/neonatal-respiratory-health-research/)
- [Cell Adhesion Molecules Research](https://scholariq.org/topics/cell-adhesion-molecules-research/)
- [Cystic Fibrosis Research Advances](https://scholariq.org/topics/cystic-fibrosis-research-advances/)
- [Immune Response and Inflammation](https://scholariq.org/topics/immune-response-and-inflammation/)
- [Glycosylation and Glycoproteins Research](https://scholariq.org/topics/glycosylation-and-glycoproteins-research/)

## Researcher university

- [Kumamoto University](https://scholariq.org/institutions/kumamoto-university/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.