# James E. Bradner

**Type:** Researchers  
**Canonical URL:** https://scholariq.org/researchers/james-e-bradner/

## Facts

| Field | Value |
| --- | --- |
| Citations | 55,390 |
| Field | Protein Degradation and Inhibitors |
| h-index | 115 |
| i10-index | 227 |
| Last Known Institution | Novartis (China) |
| OpenAlex ID | https://openalex.org/A5110274677 |
| Works | 554 |

## Researcher papers

- [Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer](https://scholariq.org/papers/response-and-resistance-to-bet-bromodomain-inhibitors-in-triple-negative-breast/)
- [A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader](https://scholariq.org/papers/a-chemoproteomic-approach-to-query-the-degradable-kinome-using-a-multi-kinase/)
- [The bromodomain protein Brd4 insulates chromatin from DNA damage signalling](https://scholariq.org/papers/the-bromodomain-protein-brd4-insulates-chromatin-from-dna-damage-signalling/)
- [DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia](https://scholariq.org/papers/dot1l-inhibits-sirt1-mediated-epigenetic-silencing-to-maintain-leukemic-gene/)
- [Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors](https://scholariq.org/papers/targeting-the-corest-complex-with-dual-histone-deacetylase-and-demethylase/)
- [AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes](https://scholariq.org/papers/af10-regulates-progressive-h3k79-methylation-and-hox-gene-expression-in-diverse/)

## Researcher topics

- [Protein Degradation and Inhibitors](https://scholariq.org/topics/protein-degradation-and-inhibitors/)
- [Histone Deacetylase Inhibitors Research](https://scholariq.org/topics/histone-deacetylase-inhibitors-research/)
- [Ubiquitin and proteasome pathways](https://scholariq.org/topics/ubiquitin-and-proteasome-pathways-2/)
- [Multiple Myeloma Research and Treatments](https://scholariq.org/topics/multiple-myeloma-research-and-treatments/)
- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)

## Researcher university

- [Novartis (China)](https://scholariq.org/institutions/novartis-china/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.