# James L. Abbruzzese

**Type:** Researchers  
**Canonical URL:** https://scholariq.org/researchers/james-l-abbruzzese/

## Facts

| Field | Value |
| --- | --- |
| Citations | 59,202 |
| Field | Pancreatic and Hepatic Oncology Research |
| h-index | 129 |
| i10-index | 448 |
| Last Known Institution | Duke Medical Center |
| OpenAlex ID | https://openalex.org/A5087376683 |
| ORCID iD | https://orcid.org/0000-0001-9223-2965 |
| Works | 780 |

## Researcher papers

- [Epidermal Growth Factor Receptor Cooperates with Signal Transducer and Activator of Transcription 3 to Induce Epithelial-Mesenchymal Transition in Cancer Cells via Up-regulation of <i>TWIST</i> Gene Expression](https://scholariq.org/papers/epidermal-growth-factor-receptor-cooperates-with-signal-transducer-and-activator/)
- [Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.](https://scholariq.org/papers/blockade-of-the-epidermal-growth-factor-receptor-signaling-by-a-novel-tyrosine/)
- [Phase II Trial of Infusional Fluorouracil, Irinotecan, and Bevacizumab for Metastatic Colorectal Cancer: Efficacy and Circulating Angiogenic Biomarkers Associated With Therapeutic Resistance](https://scholariq.org/papers/phase-ii-trial-of-infusional-fluorouracil-irinotecan-and-bevacizumab-for/)
- [Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms.](https://scholariq.org/papers/epidermal-growth-factor-receptor-blockade-with-c225-plus-gemcitabine-results-in/)
- [Rapid-fractionation preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for resectable pancreatic adenocarcinoma.](https://scholariq.org/papers/rapid-fractionation-preoperative-chemoradiation-pancreaticoduodenectomy-and/)

## Researcher topics

- [Pancreatic and Hepatic Oncology Research](https://scholariq.org/topics/pancreatic-and-hepatic-oncology-research/)
- [Colorectal Cancer Treatments and Studies](https://scholariq.org/topics/colorectal-cancer-treatments-and-studies/)
- [Cancer Genomics and Diagnostics](https://scholariq.org/topics/cancer-genomics-and-diagnostics/)
- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)
- [Gastric Cancer Management and Outcomes](https://scholariq.org/topics/gastric-cancer-management-and-outcomes/)

## Researcher university

- [Duke Medical Center](https://scholariq.org/institutions/duke-medical-center/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.