# Lewis C. Cantley

**Type:** Researchers  
**Canonical URL:** https://scholariq.org/researchers/lewis-c-cantley/

## Facts

| Field | Value |
| --- | --- |
| Citations | 207,201 |
| Field | PI3K/AKT/mTOR signaling in cancer |
| h-index | 216 |
| i10-index | 670 |
| Last Known Institution | Harvard University |
| OpenAlex ID | https://openalex.org/A5057032257 |
| ORCID iD | https://orcid.org/0000-0002-1298-7653 |
| Works | 1,369 |

## Researcher papers

- [<i>MET</i> Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling](https://scholariq.org/papers/i-met-i-amplification-leads-to-gefitinib-resistance-in-lung-cancer-by-activating/)
- [The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism](https://scholariq.org/papers/the-evolution-of-phosphatidylinositol-3-kinases-as-regulators-of-growth-and/)
- [Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism](https://scholariq.org/papers/oncogenic-kras-maintains-pancreatic-tumors-through-regulation-of-anabolic/)
- [Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function](https://scholariq.org/papers/oncogene-ablation-resistant-pancreatic-cancer-cells-depend-on-mitochondrial/)
- [Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis](https://scholariq.org/papers/phosphoglycerate-dehydrogenase-diverts-glycolytic-flux-and-contributes-to/)
- [A colorectal cancer classification system that associates cellular phenotype and responses to therapy](https://scholariq.org/papers/a-colorectal-cancer-classification-system-that-associates-cellular-phenotype-and/)
- [The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor](https://scholariq.org/papers/the-phd-finger-of-the-chromatin-associated-protein-ing2-functions-as-a-nuclear/)
- [A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response](https://scholariq.org/papers/a-murine-lung-cancer-co-clinical-trial-identifies-genetic-modifiers-of/)
- [Phosphoinositide 3-Kinase Regulates Glycolysis through Mobilization of Aldolase from the Actin Cytoskeleton](https://scholariq.org/papers/phosphoinositide-3-kinase-regulates-glycolysis-through-mobilization-of-aldolase/)
- [Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus](https://scholariq.org/papers/cell-cycle-regulated-activation-of-akt-kinase-by-phosphorylation-at-its-carboxyl/)
- [Olaparib and α-specific PI3K inhibitor alpelisib for patients with epithelial ovarian cancer: a dose-escalation and dose-expansion phase 1b trial](https://scholariq.org/papers/olaparib-and-specific-pi3k-inhibitor-alpelisib-for-patients-with-epithelial/)
- [Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in <i>LKB1</i> -Mutant Lung Cancer](https://scholariq.org/papers/metabolic-and-functional-genomic-studies-identify-deoxythymidylate-kinase-as-a/)

## Researcher topics

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)
- [Protein Kinase Regulation and GTPase Signaling](https://scholariq.org/topics/protein-kinase-regulation-and-gtpase-signaling/)
- [Metabolism, Diabetes, and Cancer](https://scholariq.org/topics/metabolism-diabetes-and-cancer/)
- [RNA modifications and cancer](https://scholariq.org/topics/rna-modifications-and-cancer/)

## Researcher university

- [Harvard University](https://scholariq.org/institutions/harvard-university/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.