# Stephen Apple

**Type:** Researchers  
**Canonical URL:** https://scholariq.org/researchers/stephen-apple/

## Facts

| Field | Value |
| --- | --- |
| Citations | 301 |
| Field | Amyotrophic Lateral Sclerosis Research |
| h-index | 8 |
| i10-index | 7 |
| Last Known Institution | Mitsubishi Group (Japan) |
| OpenAlex ID | https://openalex.org/A5016753156 |
| ORCID iD | 0000-0002-3051-3953 |
| Works | 34 |

## Researcher papers

- [Long‐term edaravone efficacy in amyotrophic lateral sclerosis: Post‐hoc analyses of Study 19 (MCI186‐19)](https://scholariq.org/papers/long-term-edaravone-efficacy-in-amyotrophic-lateral-sclerosis-post-hoc-analyses/)
- [Clinical staging in amyotrophic lateral sclerosis: analysis of Edaravone Study 19](https://scholariq.org/papers/clinical-staging-in-amyotrophic-lateral-sclerosis-analysis-of-edaravone-study-19/)
- [Edaravone efficacy in amyotrophic lateral sclerosis with reduced forced vital capacity: Post-hoc analysis of Study 19 (MCI186-19) \[clinical trial NCT01492686\]](https://scholariq.org/papers/edaravone-efficacy-in-amyotrophic-lateral-sclerosis-with-reduced-forced-vital/)
- [Oral edaravone demonstrated a favorable safety profile in patients with amyotrophic lateral sclerosis after 48 weeks of treatment](https://scholariq.org/papers/oral-edaravone-demonstrated-a-favorable-safety-profile-in-patients-with/)
- [Pharmacokinetics, Bioavailability, and Swallowing Safety With Riluzole Oral Film](https://scholariq.org/papers/pharmacokinetics-bioavailability-and-swallowing-safety-with-riluzole-oral-film/)
- [<i>Post-hoc</i> analyses of the edaravone clinical trials Study 16 and Study 19: a step toward more efficient clinical trial designs in amyotrophic lateral sclerosis](https://scholariq.org/papers/i-post-hoc-i-analyses-of-the-edaravone-clinical-trials-study-16-and-study-19-a/)
- [Analysis of the US Safety Data for Edaravone (Radicava®) From the Third Year After Launch](https://scholariq.org/papers/analysis-of-the-us-safety-data-for-edaravone-radicava-from-the-third-year-after/)
- [The effects of intervention with intravenous edaravone in Study 19 on hospitalization, tracheostomy, ventilation, and death in patients with amyotrophic lateral sclerosis](https://scholariq.org/papers/the-effects-of-intervention-with-intravenous-edaravone-in-study-19-on/)
- [Slowing the loss of physical function in amyotrophic lateral sclerosis with edaravone: Post hoc analysis of <scp>ALSFRS‐R</scp> item scores in pivotal study <scp>MCI186</scp>‐19](https://scholariq.org/papers/slowing-the-loss-of-physical-function-in-amyotrophic-lateral-sclerosis-with/)
- [Efficacy of Radicava® IV (intravenous edaravone) in subjects with differing trajectories of disease progression in amyotrophic lateral sclerosis: Use of a novel statistical approach for post hoc analysis of a pivotal phase 3 clinical trial](https://scholariq.org/papers/efficacy-of-radicava-iv-intravenous-edaravone-in-subjects-with-differing/)

## Researcher topics

- [Amyotrophic Lateral Sclerosis Research](https://scholariq.org/topics/amyotrophic-lateral-sclerosis-research/)
- [Genetic Neurodegenerative Diseases](https://scholariq.org/topics/genetic-neurodegenerative-diseases/)
- [Neurogenetic and Muscular Disorders Research](https://scholariq.org/topics/neurogenetic-and-muscular-disorders-research/)
- [Prion Diseases and Protein Misfolding](https://scholariq.org/topics/prion-diseases-and-protein-misfolding/)
- [Multiple Sclerosis Research Studies](https://scholariq.org/topics/multiple-sclerosis-research-studies/)

## Researcher university

- [Mitsubishi Group (Japan)](https://scholariq.org/institutions/mitsubishi-group-japan/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.