# Adenosine and Purinergic Signaling

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/adenosine-and-purinergic-signaling/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the molecular physiology and pharmacology of purinergic signalling, including the role of adenosine receptors, P2X receptors, and nucleotide signalling in immune suppression, inflammation, neuroprotection, and the tumor microenvironment. It explores the potential therapeutic targets related to purinergic signalling. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t11193 |
| Works | 157 |

## Topic papers all

Showing 15 of 157.

- [Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study](https://scholariq.org/papers/cannabis-use-in-adolescence-and-risk-for-adult-psychosis-longitudinal/)
- [Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression](https://scholariq.org/papers/expression-of-ectonucleotidase-cd39-by-foxp3-treg-cells-hydrolysis-of/)
- [Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis](https://scholariq.org/papers/pannexin-1-channels-mediate-find-me-signal-release-and-membrane-permeability/)
- [Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2](https://scholariq.org/papers/early-onset-stroke-and-vasculopathy-associated-with-mutations-in-ada2/)
- [Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis](https://scholariq.org/papers/serpins-promote-cancer-cell-survival-and-vascular-co-option-in-brain-metastasis/)
- [(2<i>R</i>)-4-Oxo-4-\[3-(Trifluoromethyl)-5,6-dihydro\[1,2,4\]triazolo\[4,3-<i>a</i>\]pyrazin- 7(8<i>H</i>)-yl\]-1-(2,4,5-trifluorophenyl)butan-2-amine:  A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes](https://scholariq.org/papers/2-i-r-i-4-oxo-4-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-i-a-i-pyrazin-7/)
- [Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference](https://scholariq.org/papers/atypical-hemolytic-uremic-syndrome-and-c3-glomerulopathy-conclusions-from-a/)
- [Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine](https://scholariq.org/papers/adenosine-a2a-but-not-a1-receptors-mediate-the-arousal-effect-of-caffeine/)
- [Innate immunity in diabetic kidney disease](https://scholariq.org/papers/innate-immunity-in-diabetic-kidney-disease/)
- [Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans](https://scholariq.org/papers/antibiotics-driven-gut-microbiome-perturbation-alters-immunity-to-vaccines-in/)
- [Vascular Superoxide Production by NAD(P)H Oxidase](https://scholariq.org/papers/vascular-superoxide-production-by-nad-p-h-oxidase/)
- [Molecular mechanisms of ATP secretion during immunogenic cell death](https://scholariq.org/papers/molecular-mechanisms-of-atp-secretion-during-immunogenic-cell-death/)
- [Adenosine receptors in the nervous system: pathophysiological implications](https://scholariq.org/papers/adenosine-receptors-in-the-nervous-system-pathophysiological-implications/)
- [Differential Effects of Endoplasmic Reticulum Stress-induced Autophagy on Cell Survival](https://scholariq.org/papers/differential-effects-of-endoplasmic-reticulum-stress-induced-autophagy-on-cell/)
- [Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate‐to‐severe plaque psoriasis over 52 weeks: a phase III, randomized controlled trial (ESTEEM 2)](https://scholariq.org/papers/efficacy-and-safety-of-apremilast-an-oral-phosphodiesterase-4-inhibitor-in/)

## Topic primary papers

Showing 15 of 51.

- [Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study](https://scholariq.org/papers/cannabis-use-in-adolescence-and-risk-for-adult-psychosis-longitudinal/)
- [Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression](https://scholariq.org/papers/expression-of-ectonucleotidase-cd39-by-foxp3-treg-cells-hydrolysis-of/)
- [Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis](https://scholariq.org/papers/pannexin-1-channels-mediate-find-me-signal-release-and-membrane-permeability/)
- [Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2](https://scholariq.org/papers/early-onset-stroke-and-vasculopathy-associated-with-mutations-in-ada2/)
- [Innate immunity in diabetic kidney disease](https://scholariq.org/papers/innate-immunity-in-diabetic-kidney-disease/)
- [Adenosine receptors in the nervous system: pathophysiological implications](https://scholariq.org/papers/adenosine-receptors-in-the-nervous-system-pathophysiological-implications/)
- [A Novel P2X7 Receptor Activator, the Human Cathelicidin-Derived Peptide LL37, Induces IL-1β Processing and Release](https://scholariq.org/papers/a-novel-p2x7-receptor-activator-the-human-cathelicidin-derived-peptide-ll37/)
- [Mediation of tubuloglomerular feedback by adenosine: Evidence from mice lacking adenosine 1 receptors](https://scholariq.org/papers/mediation-of-tubuloglomerular-feedback-by-adenosine-evidence-from-mice-lacking/)
- [BG9719 (CVT-124), an A <sub>1</sub> Adenosine Receptor Antagonist, Protects Against the Decline in Renal Function Observed With Diuretic Therapy](https://scholariq.org/papers/bg9719-cvt-124-an-a-sub-1-sub-adenosine-receptor-antagonist-protects-against-the/)
- [Impaired flow-dependent control of vascular tone and remodeling in P2X4-deficient mice](https://scholariq.org/papers/impaired-flow-dependent-control-of-vascular-tone-and-remodeling-in-p2x4/)
- [ADA2 deficiency (DADA2) as an unrecognised cause of early onset polyarteritis nodosa and stroke: a multicentre national study](https://scholariq.org/papers/ada2-deficiency-dada2-as-an-unrecognised-cause-of-early-onset-polyarteritis/)
- [ATP-stimulated Release of Interleukin (IL)-1β and IL-18 Requires Priming by Lipopolysaccharide and Is Independent of Caspase-1 Cleavage](https://scholariq.org/papers/atp-stimulated-release-of-interleukin-il-1-and-il-18-requires-priming-by/)
- [Identification and characterization of splice variants of the human P2X7 ATP channel](https://scholariq.org/papers/identification-and-characterization-of-splice-variants-of-the-human-p2x7-atp/)
- [Caffeine and the dopaminergic system](https://scholariq.org/papers/caffeine-and-the-dopaminergic-system/)
- [Adenosine hypothesis of schizophrenia – Opportunities for pharmacotherapy](https://scholariq.org/papers/adenosine-hypothesis-of-schizophrenia-opportunities-for-pharmacotherapy/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.