# Adipose Tissue and Metabolism

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/adipose-tissue-and-metabolism/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the function and physiological significance of brown adipose tissue, including its role in thermogenesis, the involvement of PGC-1a and UCP1, mitochondrial dysfunction, insulin resistance, beige adipocytes, metabolic regulation, and the impact of exercise on brown adipose tissue. The papers also explore the molecular mechanisms underlying adaptive thermogenesis and the potential therapeutic implications for metabolic disorders. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t11457 |
| Works | 569 |

## Topic papers all

Showing 15 of 569.

- [Mechanisms linking obesity to insulin resistance and type 2 diabetes](https://scholariq.org/papers/mechanisms-linking-obesity-to-insulin-resistance-and-type-2-diabetes/)
- [Increased oxidative stress in obesity and its impact on metabolic syndrome](https://scholariq.org/papers/increased-oxidative-stress-in-obesity-and-its-impact-on-metabolic-syndrome/)
- [Genetic studies of body mass index yield new insights for obesity biology](https://scholariq.org/papers/genetic-studies-of-body-mass-index-yield-new-insights-for-obesity-biology/)
- [The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity](https://scholariq.org/papers/the-fat-derived-hormone-adiponectin-reverses-insulin-resistance-associated-with/)
- [Identification and Importance of Brown Adipose Tissue in Adult Humans](https://scholariq.org/papers/identification-and-importance-of-brown-adipose-tissue-in-adult-humans/)
- [Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase](https://scholariq.org/papers/adiponectin-stimulates-glucose-utilization-and-fatty-acid-oxidation-by/)
- [Autophagy regulates lipid metabolism](https://scholariq.org/papers/autophagy-regulates-lipid-metabolism/)
- [Cloning of adiponectin receptors that mediate antidiabetic metabolic effects](https://scholariq.org/papers/cloning-of-adiponectin-receptors-that-mediate-antidiabetic-metabolic-effects/)
- [Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy](https://scholariq.org/papers/foxo-transcription-factors-induce-the-atrophy-related-ubiquitin-ligase-atrogin-1/)
- [Mechanisms linking obesity with cardiovascular disease](https://scholariq.org/papers/mechanisms-linking-obesity-with-cardiovascular-disease/)
- [Adiponectin and Adiponectin Receptors](https://scholariq.org/papers/adiponectin-and-adiponectin-receptors/)
- [C-Reactive Protein in Healthy Subjects: Associations With Obesity, Insulin Resistance, and Endothelial Dysfunction](https://scholariq.org/papers/c-reactive-protein-in-healthy-subjects-associations-with-obesity-insulin/)
- [The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease](https://scholariq.org/papers/the-anti-inflammatory-effects-of-exercise-mechanisms-and-implications-for-the/)
- [Dynamics of fat cell turnover in humans](https://scholariq.org/papers/dynamics-of-fat-cell-turnover-in-humans/)
- [Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice](https://scholariq.org/papers/butyrate-improves-insulin-sensitivity-and-increases-energy-expenditure-in-mice/)

## Topic primary papers

Showing 15 of 141.

- [Mechanisms linking obesity to insulin resistance and type 2 diabetes](https://scholariq.org/papers/mechanisms-linking-obesity-to-insulin-resistance-and-type-2-diabetes/)
- [Identification and Importance of Brown Adipose Tissue in Adult Humans](https://scholariq.org/papers/identification-and-importance-of-brown-adipose-tissue-in-adult-humans/)
- [Dynamics of fat cell turnover in humans](https://scholariq.org/papers/dynamics-of-fat-cell-turnover-in-humans/)
- [Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice](https://scholariq.org/papers/butyrate-improves-insulin-sensitivity-and-increases-energy-expenditure-in-mice/)
- [Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance](https://scholariq.org/papers/mitochondrial-dysfunction-in-the-elderly-possible-role-in-insulin-resistance/)
- [Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist](https://scholariq.org/papers/activation-of-human-brown-adipose-tissue-by-a-3-adrenergic-receptor-agonist/)
- [Adiponectin and AdipoR1 regulate PGC-1α and mitochondria by Ca2+ and AMPK/SIRT1](https://scholariq.org/papers/adiponectin-and-adipor1-regulate-pgc-1-and-mitochondria-by-ca2-and-ampk-sirt1/)
- [Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models](https://scholariq.org/papers/exercise-linked-fndc5-irisin-rescues-synaptic-plasticity-and-memory-defects-in/)
- [Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.](https://scholariq.org/papers/intramyocellular-triglyceride-content-is-a-determinant-of-in-vivo-insulin/)
- [Trends in insulin resistance: insights into mechanisms and therapeutic strategy](https://scholariq.org/papers/trends-in-insulin-resistance-insights-into-mechanisms-and-therapeutic-strategy/)
- [Cold acclimation recruits human brown fat and increases nonshivering thermogenesis](https://scholariq.org/papers/cold-acclimation-recruits-human-brown-fat-and-increases-nonshivering/)
- [Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans](https://scholariq.org/papers/irisin-and-fgf21-are-cold-induced-endocrine-activators-of-brown-fat-function-in/)
- [Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin Resistance](https://scholariq.org/papers/irisin-is-expressed-and-produced-by-human-muscle-and-adipose-tissue-in/)
- [Brown Adipose Tissue Improves Whole-Body Glucose Homeostasis and Insulin Sensitivity in Humans](https://scholariq.org/papers/brown-adipose-tissue-improves-whole-body-glucose-homeostasis-and-insulin/)
- [Irisin Stimulates Browning of White Adipocytes Through Mitogen-Activated Protein Kinase p38 MAP Kinase and ERK MAP Kinase Signaling](https://scholariq.org/papers/irisin-stimulates-browning-of-white-adipocytes-through-mitogen-activated-protein/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.