# Alkaloids: synthesis and pharmacology

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/alkaloids-synthesis-and-pharmacology/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the pharmacology, synthesis, and effects of kratom alkaloids, particularly those derived from Mitragyna speciosa. It covers topics such as opioid withdrawal, neuropharmacological effects, total synthesis of alkaloids, traditional medicine usage, and toxicological studies. |
| Domain | Life Sciences |
| Field | Pharmacology, Toxicology and Pharmaceutics |
| OpenAlex ID | t12649 |
| Works | 42 |

## Topic papers all

Showing 15 of 42.

- [St John's wort for depression—an overview and meta-analysis of randomised clinical trials](https://scholariq.org/papers/st-john-s-wort-for-depression-an-overview-and-meta-analysis-of-randomised/)
- [Berberine and Its More Biologically Available Derivative, Dihydroberberine, Inhibit Mitochondrial Respiratory Complex I](https://scholariq.org/papers/berberine-and-its-more-biologically-available-derivative-dihydroberberine/)
- [St John's wort for major depression](https://scholariq.org/papers/st-john-s-wort-for-major-depression/)
- [An overview of systematic reviews of pharmacological and non-pharmacological interventions for the treatment of behavioral and psychological symptoms of dementia](https://scholariq.org/papers/an-overview-of-systematic-reviews-of-pharmacological-and-non-pharmacological/)
- [Efficient Syntheses of Korupensamines A, B and Michellamine B by Asymmetric Suzuki-Miyaura Coupling Reactions](https://scholariq.org/papers/efficient-syntheses-of-korupensamines-a-b-and-michellamine-b-by-asymmetric/)
- [A six‐month double‐blind, randomized, placebo‐controlled study of a transdermal patch in Alzheimer's disease–– rivastigmine patch <i>versus</i> capsule](https://scholariq.org/papers/a-six-month-double-blind-randomized-placebo-controlled-study-of-a-transdermal/)
- [Indole alkaloid biosynthesis in <i>Catharanthus roseus</i>: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase](https://scholariq.org/papers/indole-alkaloid-biosynthesis-in-i-catharanthus-roseus-i-new-enzyme-activities/)
- [A systematic review of St. John’s wort for major depressive disorder](https://scholariq.org/papers/a-systematic-review-of-st-john-s-wort-for-major-depressive-disorder/)
- [(−)-Linalool produces antinociception in two experimental models of pain](https://scholariq.org/papers/linalool-produces-antinociception-in-two-experimental-models-of-pain/)
- [From Qinghao, Marvelous Herb of Antiquity, to the Antimalarial Trioxane Qinghaosuand Some Remarkable New Chemistry](https://scholariq.org/papers/from-qinghao-marvelous-herb-of-antiquity-to-the-antimalarial-trioxane/)
- [A scalable platform to identify fungal secondary metabolites and their gene clusters](https://scholariq.org/papers/a-scalable-platform-to-identify-fungal-secondary-metabolites-and-their-gene/)
- [Berberine modulates AP-1 activity to suppress HPV transcription and downstream signaling to induce growth arrest and apoptosis in cervical cancer cells](https://scholariq.org/papers/berberine-modulates-ap-1-activity-to-suppress-hpv-transcription-and-downstream/)
- [Berberine and Its Metabolites: Relationship between Physicochemical Properties and Plasma Levels after Administration to Human Subjects](https://scholariq.org/papers/berberine-and-its-metabolites-relationship-between-physicochemical-properties/)
- [A possible mechanism for anxiolytic and antidepressant effects of alpha- and beta-amyrin from Protium heptaphyllum (Aubl.) March](https://scholariq.org/papers/a-possible-mechanism-for-anxiolytic-and-antidepressant-effects-of-alpha-and-beta/)
- [Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. Don: A comparative review on traditional uses, phytochemistry and pharmacology](https://scholariq.org/papers/alstonia-scholaris-l-r-br-and-alstonia-macrophylla-wall-ex-g-don-a-comparative/)

## Topic primary papers

- [Indole alkaloid biosynthesis in <i>Catharanthus roseus</i>: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase](https://scholariq.org/papers/indole-alkaloid-biosynthesis-in-i-catharanthus-roseus-i-new-enzyme-activities/)
- [Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. Don: A comparative review on traditional uses, phytochemistry and pharmacology](https://scholariq.org/papers/alstonia-scholaris-l-r-br-and-alstonia-macrophylla-wall-ex-g-don-a-comparative/)
- [Effect of Yi-Gan San on psychiatric symptoms and sleep structure at patients with behavioral and psychological symptoms of dementia](https://scholariq.org/papers/effect-of-yi-gan-san-on-psychiatric-symptoms-and-sleep-structure-at-patients/)
- [Induction of apoptosis by Uncaria tomentosa through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia cells](https://scholariq.org/papers/induction-of-apoptosis-by-uncaria-tomentosa-through-reactive-oxygen-species/)
- [Successful treatment with Yi-Gan San for rapid eye movement sleep behavior disorder](https://scholariq.org/papers/successful-treatment-with-yi-gan-san-for-rapid-eye-movement-sleep-behavior/)
- [Yi-Gan San as Adjunctive Therapy for Treatment-Resistant Schizophrenia](https://scholariq.org/papers/yi-gan-san-as-adjunctive-therapy-for-treatment-resistant-schizophrenia/)
- [Successful treatment with Yi-Gan San for psychosis and sleep disturbance in a patient with dementia with Lewy bodies](https://scholariq.org/papers/successful-treatment-with-yi-gan-san-for-psychosis-and-sleep-disturbance-in-a/)
- [Monoterpenoid indole alkaloids from Gardneria multiflora](https://scholariq.org/papers/monoterpenoid-indole-alkaloids-from-gardneria-multiflora/)
- [Death associated with brorphine, an emerging novel synthetic opioid](https://scholariq.org/papers/death-associated-with-brorphine-an-emerging-novel-synthetic-opioid/)
- [Phytochemical analysis and high‐performance thin‐layer chromatography guided quantification of Boeravinone B from <i>Boerhaavia diffusa</i> root extracts: Assessment of in vitro safety analysis](https://scholariq.org/papers/phytochemical-analysis-and-high-performance-thin-layer-chromatography-guided/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.