# Alzheimer's disease research and treatments

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/alzheimer-s-disease-research-and-treatments/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the research and mechanisms related to Alzheimer's disease, including the amyloid hypothesis, tau pathology, protein misfolding, neuroinflammation, synaptic dysfunction, oxidative stress, genetic associations, Aß oligomers, neurodegeneration, and therapeutic strategies. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t10086 |
| Works | 798 |

## Topic papers all

Showing 15 of 798.

- [The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease](https://scholariq.org/papers/the-diagnosis-of-mild-cognitive-impairment-due-to-alzheimer-s-disease/)
- [Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease](https://scholariq.org/papers/toward-defining-the-preclinical-stages-of-alzheimer-s-disease-recommendations/)
- [Lecanemab in Early Alzheimer’s Disease](https://scholariq.org/papers/lecanemab-in-early-alzheimer-s-disease/)
- [Frontotemporal lobar degeneration](https://scholariq.org/papers/frontotemporal-lobar-degeneration/)
- [Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease](https://scholariq.org/papers/meta-analysis-of-74-046-individuals-identifies-11-new-susceptibility-loci-for/)
- [Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS–ADRDA criteria](https://scholariq.org/papers/research-criteria-for-the-diagnosis-of-alzheimer-s-disease-revising-the-nincds/)
- [Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease](https://scholariq.org/papers/cloning-of-a-gene-bearing-missense-mutations-in-early-onset-familial-alzheimer-s/)
- [Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB)](https://scholariq.org/papers/consensus-guidelines-for-the-clinical-and-pathologic-diagnosis-of-dementia-with/)
- [Mild cognitive impairment](https://scholariq.org/papers/mild-cognitive-impairment-2/)
- [Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease](https://scholariq.org/papers/clinical-and-biomarker-changes-in-dominantly-inherited-alzheimer-s-disease/)
- [Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease](https://scholariq.org/papers/genome-wide-association-study-identifies-variants-at-clu-and-picalm-associated/)
- [Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria](https://scholariq.org/papers/advancing-research-diagnostic-criteria-for-alzheimer-s-disease-the-iwg-2/)
- [Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing](https://scholariq.org/papers/genetic-meta-analysis-of-diagnosed-alzheimer-s-disease-identifies-new-risk-loci/)
- [A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease](https://scholariq.org/papers/a-conceptual-framework-for-research-on-subjective-cognitive-decline-in/)
- [Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis](https://scholariq.org/papers/patisiran-an-rnai-therapeutic-for-hereditary-transthyretin-amyloidosis/)

## Topic primary papers

Showing 15 of 282.

- [Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease](https://scholariq.org/papers/toward-defining-the-preclinical-stages-of-alzheimer-s-disease-recommendations/)
- [Lecanemab in Early Alzheimer’s Disease](https://scholariq.org/papers/lecanemab-in-early-alzheimer-s-disease/)
- [Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease](https://scholariq.org/papers/meta-analysis-of-74-046-individuals-identifies-11-new-susceptibility-loci-for/)
- [Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease](https://scholariq.org/papers/cloning-of-a-gene-bearing-missense-mutations-in-early-onset-familial-alzheimer-s/)
- [Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing](https://scholariq.org/papers/genetic-meta-analysis-of-diagnosed-alzheimer-s-disease-identifies-new-risk-loci/)
- [Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease](https://scholariq.org/papers/secreted-amyloid-protein-similar-to-that-in-the-senile-plaques-of-alzheimer-s/)
- [Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus](https://scholariq.org/papers/candidate-gene-for-the-chromosome-1-familial-alzheimer-s-disease-locus/)
- [Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease](https://scholariq.org/papers/genome-wide-association-study-identifies-variants-at-clu-and-cr1-associated-with/)
- [Risk of dementia in diabetes mellitus: a systematic review](https://scholariq.org/papers/risk-of-dementia-in-diabetes-mellitus-a-systematic-review/)
- [Copper, iron and zinc in Alzheimer's disease senile plaques](https://scholariq.org/papers/copper-iron-and-zinc-in-alzheimer-s-disease-senile-plaques/)
- [Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature](https://scholariq.org/papers/correlation-of-alzheimer-disease-neuropathologic-changes-with-cognitive-status-a/)
- [Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease](https://scholariq.org/papers/common-variants-at-abca7-ms4a6a-ms4a4e-epha1-cd33-and-cd2ap-are-associated-with/)
- [Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function](https://scholariq.org/papers/tau-suppression-in-a-neurodegenerative-mouse-model-improves-memory-function/)
- [Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease](https://scholariq.org/papers/common-variants-at-ms4a4-ms4a6e-cd2ap-cd33-and-epha1-are-associated-with-late/)
- [Twenty Years of the Alzheimer’s Disease Amyloid Hypothesis: A Genetic Perspective](https://scholariq.org/papers/twenty-years-of-the-alzheimer-s-disease-amyloid-hypothesis-a-genetic-perspective/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.