# Amyotrophic Lateral Sclerosis Research
**Type:** Topics
**Canonical URL:** https://scholariq.org/topics/amyotrophic-lateral-sclerosis-research/
## Facts
| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the molecular mechanisms, genetics, and pathology of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). It covers topics such as TDP-43, FUS/TLS, C9ORF72 mutations, neurodegeneration of motor neurons, RNA processing, progranulin deficiency, ubiquitin-positive inclusions, and the genetic underpinnings of these diseases. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t10855 |
| Works | 471 |
## Topic papers all
Showing 15 of 471.
- [Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis](https://scholariq.org/papers/mutations-in-cu-zn-superoxide-dismutase-gene-are-associated-with-familial/)
- [Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis](https://scholariq.org/papers/ubiquitinated-tdp-43-in-frontotemporal-lobar-degeneration-and-amyotrophic/)
- [El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis](https://scholariq.org/papers/el-escorial-revisited-revised-criteria-for-the-diagnosis-of-amyotrophic-lateral/)
- [Global prevalence of dementia: a Delphi consensus study](https://scholariq.org/papers/global-prevalence-of-dementia-a-delphi-consensus-study/)
- [Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia](https://scholariq.org/papers/sensitivity-of-revised-diagnostic-criteria-for-the-behavioural-variant-of/)
- [Frontotemporal lobar degeneration](https://scholariq.org/papers/frontotemporal-lobar-degeneration/)
- [Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS](https://scholariq.org/papers/expanded-ggggcc-hexanucleotide-repeat-in-noncoding-region-of-c9orf72-causes/)
- [A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD](https://scholariq.org/papers/a-hexanucleotide-repeat-expansion-in-c9orf72-is-the-cause-of-chromosome-9p21/)
- [Second consensus statement on the diagnosis of multiple system atrophy](https://scholariq.org/papers/second-consensus-statement-on-the-diagnosis-of-multiple-system-atrophy/)
- [Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis](https://scholariq.org/papers/mutations-in-the-i-fus-tls-i-gene-on-chromosome-16-cause-familial-amyotrophic/)
- [Amyotrophic lateral sclerosis](https://scholariq.org/papers/amyotrophic-lateral-sclerosis/)
- [Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy](https://scholariq.org/papers/nusinersen-versus-sham-control-in-infantile-onset-spinal-muscular-atrophy/)
- [Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report](https://scholariq.org/papers/limbic-predominant-age-related-tdp-43-encephalopathy-late-consensus-working/)
- [State of play in amyotrophic lateral sclerosis genetics](https://scholariq.org/papers/state-of-play-in-amyotrophic-lateral-sclerosis-genetics/)
- [TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis](https://scholariq.org/papers/tardbp-mutations-in-individuals-with-sporadic-and-familial-amyotrophic-lateral/)
## Topic primary papers
Showing 15 of 314.
- [Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis](https://scholariq.org/papers/mutations-in-cu-zn-superoxide-dismutase-gene-are-associated-with-familial/)
- [Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis](https://scholariq.org/papers/ubiquitinated-tdp-43-in-frontotemporal-lobar-degeneration-and-amyotrophic/)
- [El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis](https://scholariq.org/papers/el-escorial-revisited-revised-criteria-for-the-diagnosis-of-amyotrophic-lateral/)
- [Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS](https://scholariq.org/papers/expanded-ggggcc-hexanucleotide-repeat-in-noncoding-region-of-c9orf72-causes/)
- [A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD](https://scholariq.org/papers/a-hexanucleotide-repeat-expansion-in-c9orf72-is-the-cause-of-chromosome-9p21/)
- [Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis](https://scholariq.org/papers/mutations-in-the-i-fus-tls-i-gene-on-chromosome-16-cause-familial-amyotrophic/)
- [Amyotrophic lateral sclerosis](https://scholariq.org/papers/amyotrophic-lateral-sclerosis/)
- [Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report](https://scholariq.org/papers/limbic-predominant-age-related-tdp-43-encephalopathy-late-consensus-working/)
- [State of play in amyotrophic lateral sclerosis genetics](https://scholariq.org/papers/state-of-play-in-amyotrophic-lateral-sclerosis-genetics/)
- [TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis](https://scholariq.org/papers/tardbp-mutations-in-individuals-with-sporadic-and-familial-amyotrophic-lateral/)
- [Amyotrophic lateral sclerosis](https://scholariq.org/papers/amyotrophic-lateral-sclerosis-3/)
- [Amyotrophic lateral sclerosis](https://scholariq.org/papers/amyotrophic-lateral-sclerosis-2/)
- [Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study](https://scholariq.org/papers/frequency-of-the-c9orf72-hexanucleotide-repeat-expansion-in-patients-with/)
- [Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS](https://scholariq.org/papers/exome-sequencing-reveals-vcp-mutations-as-a-cause-of-familial-als/)
- [Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia](https://scholariq.org/papers/mutations-in-ubqln2-cause-dominant-x-linked-juvenile-and-adult-onset-als-and-als/)
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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.