# Anesthesia and Neurotoxicity Research

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/anesthesia-and-neurotoxicity-research/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on the neurotoxic effects of anesthetic agents, particularly during early development, leading to neuronal apoptosis, cognitive impairment, and altered synaptic plasticity. The research explores the long-term neurodevelopmental outcomes and potential learning disabilities associated with early exposure to general anesthetics, highlighting concerns about the impact on brain development. |
| Domain | Life Sciences |
| Field | Neuroscience |
| OpenAlex ID | t12963 |
| Works | 195 |

## Topic papers all

Showing 15 of 195.

- [Adverse childhood experiences, allostasis, allostatic load, and age-related disease](https://scholariq.org/papers/adverse-childhood-experiences-allostasis-allostatic-load-and-age-related-disease/)
- [Neurobehavioural effects of developmental toxicity](https://scholariq.org/papers/neurobehavioural-effects-of-developmental-toxicity/)
- [Part 4: Advanced Life Support](https://scholariq.org/papers/part-4-advanced-life-support/)
- [Early Exposure to Anesthesia and Learning Disabilities in a Population-based Birth Cohort](https://scholariq.org/papers/early-exposure-to-anesthesia-and-learning-disabilities-in-a-population-based/)
- [A Review of Indocyanine Green Fluorescent Imaging in Surgery](https://scholariq.org/papers/a-review-of-indocyanine-green-fluorescent-imaging-in-surgery/)
- [Delirium](https://scholariq.org/papers/delirium/)
- [The cellular neurobiology of depression](https://scholariq.org/papers/the-cellular-neurobiology-of-depression/)
- [Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial](https://scholariq.org/papers/neurodevelopmental-outcome-at-2-years-of-age-after-general-anaesthesia-and-awake/)
- [European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium](https://scholariq.org/papers/european-society-of-anaesthesiology-evidence-based-and-consensus-based-guideline/)
- [Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood](https://scholariq.org/papers/association-between-a-single-general-anesthesia-exposure-before-age-36-months/)
- [Cognitive and Behavioral Outcomes After Early Exposure to Anesthesia and Surgery](https://scholariq.org/papers/cognitive-and-behavioral-outcomes-after-early-exposure-to-anesthesia-and-surgery/)
- [Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial](https://scholariq.org/papers/neurodevelopmental-outcome-at-5-years-of-age-after-general-anaesthesia-or-awake/)
- [The Incidence of Awareness During Anesthesia: A Multicenter United States Study](https://scholariq.org/papers/the-incidence-of-awareness-during-anesthesia-a-multicenter-united-states-study/)
- [Delirium in the intensive care unit](https://scholariq.org/papers/delirium-in-the-intensive-care-unit/)
- [Long-term Differences in Language and Cognitive Function After Childhood Exposure to Anesthesia](https://scholariq.org/papers/long-term-differences-in-language-and-cognitive-function-after-childhood/)

## Topic primary papers

Showing 15 of 35.

- [Neurobehavioural effects of developmental toxicity](https://scholariq.org/papers/neurobehavioural-effects-of-developmental-toxicity/)
- [Early Exposure to Anesthesia and Learning Disabilities in a Population-based Birth Cohort](https://scholariq.org/papers/early-exposure-to-anesthesia-and-learning-disabilities-in-a-population-based/)
- [Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial](https://scholariq.org/papers/neurodevelopmental-outcome-at-2-years-of-age-after-general-anaesthesia-and-awake/)
- [Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood](https://scholariq.org/papers/association-between-a-single-general-anesthesia-exposure-before-age-36-months/)
- [Cognitive and Behavioral Outcomes After Early Exposure to Anesthesia and Surgery](https://scholariq.org/papers/cognitive-and-behavioral-outcomes-after-early-exposure-to-anesthesia-and-surgery/)
- [Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial](https://scholariq.org/papers/neurodevelopmental-outcome-at-5-years-of-age-after-general-anaesthesia-or-awake/)
- [Long-term Differences in Language and Cognitive Function After Childhood Exposure to Anesthesia](https://scholariq.org/papers/long-term-differences-in-language-and-cognitive-function-after-childhood/)
- [Neuropsychological and Behavioral Outcomes after Exposure of Young Children to Procedures Requiring General Anesthesia](https://scholariq.org/papers/neuropsychological-and-behavioral-outcomes-after-exposure-of-young-children-to/)
- [Early Childhood Exposure to Anesthesia and Risk of Developmental and Behavioral Disorders in a Sibling Birth Cohort](https://scholariq.org/papers/early-childhood-exposure-to-anesthesia-and-risk-of-developmental-and-behavioral/)
- [A Retrospective Cohort Study of the Association of Anesthesia and Hernia Repair Surgery With Behavioral and Developmental Disorders in Young Children](https://scholariq.org/papers/a-retrospective-cohort-study-of-the-association-of-anesthesia-and-hernia-repair/)
- [Pharmacological Aspects and Potential New Clinical Applications of Ketamine: Reevaluation of an Old Drug](https://scholariq.org/papers/pharmacological-aspects-and-potential-new-clinical-applications-of-ketamine/)
- [LPS-induced muscularis macrophage nitric oxide suppresses rat jejunal circular muscle activity](https://scholariq.org/papers/lps-induced-muscularis-macrophage-nitric-oxide-suppresses-rat-jejunal-circular/)
- [Effect of General Anesthesia in Infancy on Long-Term Recognition Memory in Humans and Rats](https://scholariq.org/papers/effect-of-general-anesthesia-in-infancy-on-long-term-recognition-memory-in/)
- [Preconditioning with Isoflurane Produces Dose-Dependent Neuroprotection via Activation of Adenosine Triphosphate-Regulated Potassium Channels After Focal Cerebral Ischemia in Rats](https://scholariq.org/papers/preconditioning-with-isoflurane-produces-dose-dependent-neuroprotection-via-2/)
- [Down-regulation of early ionotrophic glutamate receptor subunit developmental expression as a mechanism for observed plasticity deficits following gestational exposure to benzo(a)pyrene](https://scholariq.org/papers/down-regulation-of-early-ionotrophic-glutamate-receptor-subunit-developmental/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.