# Animal testing and alternatives

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/animal-testing-and-alternatives/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers focuses on improving the reporting and conduct of animal research studies, with an emphasis on the use of ARRIVE guidelines, cytotoxicity assays, ethical considerations, systematic reviews, in vitro testing methods, and addressing publication bias. It also discusses the challenges in translating findings from animal studies to human applications and the determination of sample sizes for preclinical studies. |
| Domain | Health Sciences |
| Field | Veterinary |
| OpenAlex ID | t12281 |
| Works | 76 |

## Topic papers all

Showing 15 of 76.

- [Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses](https://scholariq.org/papers/hormones-and-endocrine-disrupting-chemicals-low-dose-effects-and-nonmonotonic/)
- [Development of the Instrument to assess the Credibility of Effect Modification Analyses (ICEMAN) in randomized controlled trials and meta-analyses](https://scholariq.org/papers/development-of-the-instrument-to-assess-the-credibility-of-effect-modification/)
- [Chapel Hill bisphenol A expert panel consensus statement: Integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure](https://scholariq.org/papers/chapel-hill-bisphenol-a-expert-panel-consensus-statement-integration-of/)
- [Proliferative and Nonproliferative Lesions of the Rat and Mouse Hepatobiliary System](https://scholariq.org/papers/proliferative-and-nonproliferative-lesions-of-the-rat-and-mouse-hepatobiliary/)
- [Human body burdens of chemicals used in plastic manufacture](https://scholariq.org/papers/human-body-burdens-of-chemicals-used-in-plastic-manufacture/)
- [Tumor measurement in the nude mouse](https://scholariq.org/papers/tumor-measurement-in-the-nude-mouse/)
- [Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010](https://scholariq.org/papers/alternative-non-animal-methods-for-cosmetics-testing-current-status-and-future/)
- [Development and validation of MIX: comprehensive free software for meta-analysis of causal research data](https://scholariq.org/papers/development-and-validation-of-mix-comprehensive-free-software-for-meta-analysis/)
- [Human exposure to bisphenol A by biomonitoring: Methods, results and assessment of environmental exposures](https://scholariq.org/papers/human-exposure-to-bisphenol-a-by-biomonitoring-methods-results-and-assessment-of/)
- [Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines](https://scholariq.org/papers/comparative-toxicity-of-24-manufactured-nanoparticles-in-human-alveolar/)
- [How much do resin-based dental materials release? A meta-analytical approach](https://scholariq.org/papers/how-much-do-resin-based-dental-materials-release-a-meta-analytical-approach/)
- [Principles and methods of toxicology](https://scholariq.org/papers/principles-and-methods-of-toxicology/)
- [Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment](https://scholariq.org/papers/integration-of-dosimetry-exposure-and-high-throughput-screening-data-in-chemical/)
- [Toxicity testing in the 21st century: progress in the past decade and future perspectives](https://scholariq.org/papers/toxicity-testing-in-the-21st-century-progress-in-the-past-decade-and-future/)
- [Adverse outcome pathways: opportunities, limitations and open questions](https://scholariq.org/papers/adverse-outcome-pathways-opportunities-limitations-and-open-questions/)

## Topic primary papers

Showing 15 of 17.

- [Tumor measurement in the nude mouse](https://scholariq.org/papers/tumor-measurement-in-the-nude-mouse/)
- [Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010](https://scholariq.org/papers/alternative-non-animal-methods-for-cosmetics-testing-current-status-and-future/)
- [Principles and methods of toxicology](https://scholariq.org/papers/principles-and-methods-of-toxicology/)
- [Risk Assessment Extrapolations and Physiological Modeling](https://scholariq.org/papers/risk-assessment-extrapolations-and-physiological-modeling/)
- [Quantitative<i>in vitro</i>to<i>in vivo</i>extrapolation of cell-based toxicity assay results](https://scholariq.org/papers/quantitative-i-in-vitro-i-to-i-in-vivo-i-extrapolation-of-cell-based-toxicity/)
- [The Use of In Vitro Toxicity Data and Physiologically Based Kinetic Modeling to Predict Dose-Response Curves for In Vivo Developmental Toxicity of Glycol Ethers in Rat and Man](https://scholariq.org/papers/the-use-of-in-vitro-toxicity-data-and-physiologically-based-kinetic-modeling-to/)
- [Methodological Rigor in Preclinical Cardiovascular Studies](https://scholariq.org/papers/methodological-rigor-in-preclinical-cardiovascular-studies/)
- [Development of a murine local lymph node assay for the determination of sensitizing potential](https://scholariq.org/papers/development-of-a-murine-local-lymph-node-assay-for-the-determination-of/)
- [Physiology and pharmacology](https://scholariq.org/papers/physiology-and-pharmacology/)
- [Veterinary toxicology](https://scholariq.org/papers/veterinary-toxicology/)
- [Retention of Inhaled Formaldehyde, Propionaldehyde, and Acrolein in the Dog](https://scholariq.org/papers/retention-of-inhaled-formaldehyde-propionaldehyde-and-acrolein-in-the-dog/)
- [Classification and reporting of severity experienced by animals used in scientific procedures: FELASA/ECLAM/ESLAV Working Group report](https://scholariq.org/papers/classification-and-reporting-of-severity-experienced-by-animals-used-in/)
- [Validating Animal Models for Preclinical Research: A Scientific and Ethical Discussion](https://scholariq.org/papers/validating-animal-models-for-preclinical-research-a-scientific-and-ethical/)
- [Sensory Irritation and Incapacitation Evoked by Thermal Decomposition Products of Polymers and Comparisons with Known Sensory Irritants](https://scholariq.org/papers/sensory-irritation-and-incapacitation-evoked-by-thermal-decomposition-products/)
- [Central Neurotransmitter Turnover](https://scholariq.org/papers/central-neurotransmitter-turnover/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
