# Apelin-related biomedical research

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/apelin-related-biomedical-research/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of apelin, a novel adipokine, and its receptor APJ in various physiological processes such as cardiovascular regulation, angiogenesis, obesity, diabetes, and neuroprotection. The research covers molecular properties, tissue distribution, signaling pathways, therapeutic potential, and pathophysiological implications of the apelin/APJ system. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t13505 |
| Works | 76 |

## Topic papers all

Showing 15 of 76.

- [Molecular Mechanisms of Human Hypertension](https://scholariq.org/papers/molecular-mechanisms-of-human-hypertension/)
- [Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction](https://scholariq.org/papers/reciprocal-relationships-between-insulin-resistance-and-endothelial-dysfunction/)
- [RESULTS FROM THE INTERNATIONAL CONFERENCE OF EXPERTS ON INTRA-ABDOMINAL HYPERTENSION AND ABDOMINAL COMPARTMENT SYNDROME](https://scholariq.org/papers/results-from-the-international-conference-of-experts-on-intra-abdominal-2/)
- [Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats.](https://scholariq.org/papers/characterization-of-protein-kinase-c-beta-isoform-activation-on-the-gene/)
- [The renin-angiotensin-aldosterone system and its suppression](https://scholariq.org/papers/the-renin-angiotensin-aldosterone-system-and-its-suppression/)
- [Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice](https://scholariq.org/papers/transgenic-amplification-of-glucocorticoid-action-in-adipose-tissue-causes-high/)
- [From Hyperglycemia to Diabetic Kidney Disease: The Role of Metabolic, Hemodynamic, Intracellular Factors and Growth Factors/Cytokines](https://scholariq.org/papers/from-hyperglycemia-to-diabetic-kidney-disease-the-role-of-metabolic-hemodynamic/)
- [Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy.](https://scholariq.org/papers/role-of-the-deletion-of-polymorphism-of-the-angiotensin-converting-enzyme-gene/)
- [Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin](https://scholariq.org/papers/physical-exercise-induced-hippocampal-neurogenesis-and-antidepressant-effects/)
- [Activation and Induction of NUR77/NURR1 in Corticotrophs by CRH/cAMP: Involvement of Calcium, Protein Kinase A, and MAPK Pathways](https://scholariq.org/papers/activation-and-induction-of-nur77-nurr1-in-corticotrophs-by-crh-camp-involvement/)
- [Resistin is secreted from macrophages in atheromas and promotes atherosclerosis](https://scholariq.org/papers/resistin-is-secreted-from-macrophages-in-atheromas-and-promotes-atherosclerosis/)
- [Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling](https://scholariq.org/papers/elabela-alleviates-ferroptosis-myocardial-remodeling-fibrosis-and-heart/)
- [Registry and Survival Study in Chinese Patients With Idiopathic and Familial Pulmonary Arterial Hypertension](https://scholariq.org/papers/registry-and-survival-study-in-chinese-patients-with-idiopathic-and-familial/)
- [TNFα up‐regulates apelin expression in human and mouse adipose tissue](https://scholariq.org/papers/tnf-up-regulates-apelin-expression-in-human-and-mouse-adipose-tissue/)
- [Neuropilin-1-mediated Vascular Permeability Factor/Vascular Endothelial Growth Factor-dependent Endothelial Cell Migration](https://scholariq.org/papers/neuropilin-1-mediated-vascular-permeability-factor-vascular-endothelial-growth/)

## Topic primary papers

- [Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling](https://scholariq.org/papers/elabela-alleviates-ferroptosis-myocardial-remodeling-fibrosis-and-heart/)
- [TNFα up‐regulates apelin expression in human and mouse adipose tissue](https://scholariq.org/papers/tnf-up-regulates-apelin-expression-in-human-and-mouse-adipose-tissue/)
- [Apelin Levels Are Increased in Morbidly Obese Subjects with Type 2 Diabetes Mellitus](https://scholariq.org/papers/apelin-levels-are-increased-in-morbidly-obese-subjects-with-type-2-diabetes/)
- [The angiotensin II receptor type 1b is the primary sensor of intraluminal pressure in cerebral artery smooth muscle cells](https://scholariq.org/papers/the-angiotensin-ii-receptor-type-1b-is-the-primary-sensor-of-intraluminal/)
- [Apelin Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells](https://scholariq.org/papers/apelin-attenuates-the-osteoblastic-differentiation-of-vascular-smooth-muscle/)
- [Serum Elabela/Toddler Levels Are Associated with Albuminuria in Patients with Type 2 Diabetes](https://scholariq.org/papers/serum-elabela-toddler-levels-are-associated-with-albuminuria-in-patients-with/)
- [Effects of adipokines and obesity on uterine contractility](https://scholariq.org/papers/effects-of-adipokines-and-obesity-on-uterine-contractility/)
- [Overexpression of Circulating Soluble Nogo-B Improves Diabetic Kidney Disease by Protecting the Vasculature](https://scholariq.org/papers/overexpression-of-circulating-soluble-nogo-b-improves-diabetic-kidney-disease-by/)
- [A novel insight into the neuroprotective effects of cannabidiol: maintained apelin/dopamine synthesis, NRF2 signaling, and AKT/CREB/BDNF gene expressions](https://scholariq.org/papers/a-novel-insight-into-the-neuroprotective-effects-of-cannabidiol-maintained/)
- [Kynurenine–PARP-1 Link Mediated by MicroRNA 210 May Be Dysregulated in Pulmonary Hypertension](https://scholariq.org/papers/kynurenine-parp-1-link-mediated-by-microrna-210-may-be-dysregulated-in-pulmonary/)
- [Disfunzione endoteliale nei pazienti con ipotiroidismo subclinico: ruolo dell’infiammazione sistemica](https://scholariq.org/papers/disfunzione-endoteliale-nei-pazienti-con-ipotiroidismo-subclinico-ruolo-dell/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.