# Autophagy in Disease and Therapy

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/autophagy-in-disease-and-therapy/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of autophagy in various diseases, including neurodegenerative diseases, cancer, and infections. It covers the molecular mechanisms, regulation, and therapeutic implications of autophagy, as well as its interactions with apoptosis, inflammation, and immunity. |
| Domain | Health Sciences |
| Field | Medicine |
| OpenAlex ID | t10587 |
| Works | 399 |

## Topic papers all

Showing 15 of 399.

- [Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)](https://scholariq.org/papers/guidelines-for-the-use-and-interpretation-of-assays-for-monitoring-autophagy-3rd/)
- [Guidelines for the use and interpretation of assays for monitoring autophagy](https://scholariq.org/papers/guidelines-for-the-use-and-interpretation-of-assays-for-monitoring-autophagy/)
- [Autophagy regulates lipid metabolism](https://scholariq.org/papers/autophagy-regulates-lipid-metabolism/)
- [Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β](https://scholariq.org/papers/caspase-12-mediates-endoplasmic-reticulum-specific-apoptosis-and-cytotoxicity-by/)
- [Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>](https://scholariq.org/papers/guidelines-for-the-use-and-interpretation-of-assays-for-monitoring-autophagy-4th/)
- [Autophagy promotes ferroptosis by degradation of ferritin](https://scholariq.org/papers/autophagy-promotes-ferroptosis-by-degradation-of-ferritin/)
- [Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy](https://scholariq.org/papers/impaired-degradation-of-mutant-synuclein-by-chaperone-mediated-autophagy/)
- [The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress](https://scholariq.org/papers/the-role-of-autophagy-in-cardiomyocytes-in-the-basal-state-and-in-response-to/)
- [A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells](https://scholariq.org/papers/a-key-role-for-autophagy-and-the-autophagy-gene-atg16l1-in-mouse-and-human/)
- [JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy](https://scholariq.org/papers/jnk1-mediated-phosphorylation-of-bcl-2-regulates-starvation-induced-autophagy/)
- [Nix is a selective autophagy receptor for mitochondrial clearance](https://scholariq.org/papers/nix-is-a-selective-autophagy-receptor-for-mitochondrial-clearance/)
- [Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure](https://scholariq.org/papers/mitochondrial-dna-that-escapes-from-autophagy-causes-inflammation-and-heart/)
- [Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis](https://scholariq.org/papers/exercise-induced-bcl2-regulated-autophagy-is-required-for-muscle-glucose/)
- [Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways](https://scholariq.org/papers/exome-sequencing-in-amyotrophic-lateral-sclerosis-identifies-risk-genes-and/)
- [HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein](https://scholariq.org/papers/hsv-1-icp34-5-confers-neurovirulence-by-targeting-the-beclin-1-autophagy-protein/)

## Topic primary papers

Showing 15 of 204.

- [Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)](https://scholariq.org/papers/guidelines-for-the-use-and-interpretation-of-assays-for-monitoring-autophagy-3rd/)
- [Guidelines for the use and interpretation of assays for monitoring autophagy](https://scholariq.org/papers/guidelines-for-the-use-and-interpretation-of-assays-for-monitoring-autophagy/)
- [Autophagy regulates lipid metabolism](https://scholariq.org/papers/autophagy-regulates-lipid-metabolism/)
- [Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>](https://scholariq.org/papers/guidelines-for-the-use-and-interpretation-of-assays-for-monitoring-autophagy-4th/)
- [The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress](https://scholariq.org/papers/the-role-of-autophagy-in-cardiomyocytes-in-the-basal-state-and-in-response-to/)
- [A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells](https://scholariq.org/papers/a-key-role-for-autophagy-and-the-autophagy-gene-atg16l1-in-mouse-and-human/)
- [JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy](https://scholariq.org/papers/jnk1-mediated-phosphorylation-of-bcl-2-regulates-starvation-induced-autophagy/)
- [Nix is a selective autophagy receptor for mitochondrial clearance](https://scholariq.org/papers/nix-is-a-selective-autophagy-receptor-for-mitochondrial-clearance/)
- [Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure](https://scholariq.org/papers/mitochondrial-dna-that-escapes-from-autophagy-causes-inflammation-and-heart/)
- [Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis](https://scholariq.org/papers/exercise-induced-bcl2-regulated-autophagy-is-required-for-muscle-glucose/)
- [HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein](https://scholariq.org/papers/hsv-1-icp34-5-confers-neurovirulence-by-targeting-the-beclin-1-autophagy-protein/)
- [Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor](https://scholariq.org/papers/prohibitin-2-is-an-inner-mitochondrial-membrane-mitophagy-receptor/)
- [Regulated cell death (RCD) in cancer: key pathways and targeted therapies](https://scholariq.org/papers/regulated-cell-death-rcd-in-cancer-key-pathways-and-targeted-therapies/)
- [Autophagy regulates adipose mass and differentiation in mice](https://scholariq.org/papers/autophagy-regulates-adipose-mass-and-differentiation-in-mice/)
- [Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation](https://scholariq.org/papers/akt-mediated-regulation-of-autophagy-and-tumorigenesis-through-beclin-1/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.