# Biochemical Acid Research Studies

**Type:** Topics  
**Canonical URL:** https://scholariq.org/topics/biochemical-acid-research-studies/

## Facts

| Field | Value |
| --- | --- |
| Description | This cluster of papers explores the role of lipoic acid in metabolism, oxidative stress, and various health conditions such as diabetes and neurodegenerative diseases. It delves into the molecular mechanisms, therapeutic potential, and regulatory effects of lipoic acid on enzymes involved in energy metabolism and antioxidant activities. Additionally, it investigates the impact of lipoic acid on mitochondrial function, inflammation, and its potential as a treatment for metabolic diseases. |
| Domain | Life Sciences |
| Field | Biochemistry, Genetics and Molecular Biology |
| OpenAlex ID | t12915 |
| Works | 78 |

## Topic papers all

Showing 15 of 78.

- [Prognostic factors in ALS: A critical review](https://scholariq.org/papers/prognostic-factors-in-als-a-critical-review/)
- [A review on the role of antioxidants in the management of diabetes and its complications](https://scholariq.org/papers/a-review-on-the-role-of-antioxidants-in-the-management-of-diabetes-and-its/)
- [Temporal Trends in Phthalate Exposures: Findings from the National Health and Nutrition Examination Survey, 2001–2010](https://scholariq.org/papers/temporal-trends-in-phthalate-exposures-findings-from-the-national-health-and/)
- [Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral Sclerosis](https://scholariq.org/papers/trial-of-sodium-phenylbutyrate-taurursodiol-for-amyotrophic-lateral-sclerosis/)
- [Oxidative stress and diabetes: antioxidative strategies](https://scholariq.org/papers/oxidative-stress-and-diabetes-antioxidative-strategies/)
- [AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function](https://scholariq.org/papers/ampk-dysregulation-promotes-diabetes-related-reduction-of-superoxide-and/)
- [COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness](https://scholariq.org/papers/coq6-mutations-in-human-patients-produce-nephrotic-syndrome-with-sensorineural/)
- [Mitochondrial dysfunction in inherited renal disease and acute kidney injury](https://scholariq.org/papers/mitochondrial-dysfunction-in-inherited-renal-disease-and-acute-kidney-injury/)
- [Mitochondrial dysfunction in the pathophysiology of renal diseases](https://scholariq.org/papers/mitochondrial-dysfunction-in-the-pathophysiology-of-renal-diseases/)
- [Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy.](https://scholariq.org/papers/effects-of-dl-alpha-lipoic-acid-on-peripheral-nerve-conduction-blood-flow-energy/)
- [Hypermetabolism in ALS patients: an early and persistent phenomenon](https://scholariq.org/papers/hypermetabolism-in-als-patients-an-early-and-persistent-phenomenon/)
- [ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption](https://scholariq.org/papers/adck4-mutations-promote-steroid-resistant-nephrotic-syndrome-through-coq10/)
- [The role of oxidative stress and NF‐κB activation in late diabetic complications](https://scholariq.org/papers/the-role-of-oxidative-stress-and-nf-b-activation-in-late-diabetic-complications/)
- [COQ2 Nephropathy](https://scholariq.org/papers/coq2-nephropathy/)
- [A Small Decrease of Plastid Transketolase Activity in Antisense Tobacco Transformants Has Dramatic Effects on Photosynthesis and Phenylpropanoid Metabolism](https://scholariq.org/papers/a-small-decrease-of-plastid-transketolase-activity-in-antisense-tobacco/)

## Topic primary papers

Showing 15 of 22.

- [Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy.](https://scholariq.org/papers/effects-of-dl-alpha-lipoic-acid-on-peripheral-nerve-conduction-blood-flow-energy/)
- [A Small Decrease of Plastid Transketolase Activity in Antisense Tobacco Transformants Has Dramatic Effects on Photosynthesis and Phenylpropanoid Metabolism](https://scholariq.org/papers/a-small-decrease-of-plastid-transketolase-activity-in-antisense-tobacco/)
- [Metabolic profiling indicates impaired pyruvate dehydrogenase function in myalgic encephalopathy/chronic fatigue syndrome](https://scholariq.org/papers/metabolic-profiling-indicates-impaired-pyruvate-dehydrogenase-function-in/)
- [Micronutrient Supplementation to Reduce Cardiovascular Risk](https://scholariq.org/papers/micronutrient-supplementation-to-reduce-cardiovascular-risk/)
- [Antioxidant Supplementation Reduces Skeletal Muscle Mitochondrial Biogenesis](https://scholariq.org/papers/antioxidant-supplementation-reduces-skeletal-muscle-mitochondrial-biogenesis/)
- [Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway](https://scholariq.org/papers/alpha-lipoic-acid-improves-high-fat-diet-induced-hepatic-steatosis-by-modulating/)
- [Biologic activity of mitochondrial metabolites on aging and age-related hearing loss](https://scholariq.org/papers/biologic-activity-of-mitochondrial-metabolites-on-aging-and-age-related-hearing/)
- [Alpha-Lipoic Acid Exerts Anti-Inflammatory Effects on Lipopolysaccharide-Stimulated Rat Mesangial Cells via Inhibition of Nuclear Factor Kappa B (NF-κB) Signaling Pathway](https://scholariq.org/papers/alpha-lipoic-acid-exerts-anti-inflammatory-effects-on-lipopolysaccharide/)
- [DCA Protects against Oxidation Injury Attributed to Cerebral Ischemia‐Reperfusion by Regulating Glycolysis through PDK2‐PDH‐Nrf2 Axis](https://scholariq.org/papers/dca-protects-against-oxidation-injury-attributed-to-cerebral-ischemia/)
- [Antioxidants: A Possible Role in Kidney Protection](https://scholariq.org/papers/antioxidants-a-possible-role-in-kidney-protection/)
- [Alpha-lipoic acid (ALA) supplementation effect on glycemic and inflammatory biomarkers: A Systematic Review and meta- analysis](https://scholariq.org/papers/alpha-lipoic-acid-ala-supplementation-effect-on-glycemic-and-inflammatory/)
- [Pyruvate Metabolism in Friedreich's Ataxia](https://scholariq.org/papers/pyruvate-metabolism-in-friedreich-s-ataxia/)
- [Effects of alpha-lipoic acid supplementation on C-reactive protein level: A systematic review and meta-analysis of randomized controlled clinical trials](https://scholariq.org/papers/effects-of-alpha-lipoic-acid-supplementation-on-c-reactive-protein-level-a/)
- [The Role of Dietary Antioxidants on Oxidative Stress in Diabetic Nephropathy.](https://scholariq.org/papers/the-role-of-dietary-antioxidants-on-oxidative-stress-in-diabetic-nephropathy/)
- [The impact of alpha-lipoic acid on amikacin-induced nephrotoxicity](https://scholariq.org/papers/the-impact-of-alpha-lipoic-acid-on-amikacin-induced-nephrotoxicity/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.